4-hydroxy-tetrahydrodipicolinate reductase [Escherichia coli].

LOCUS       WP_000543582             273 aa            linear   BCT 29-APR-2021
ACCESSION   WP_000543582
VERSION     WP_000543582.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 273)
  AUTHORS   Scapin,G., Reddy,S.G., Zheng,R. and Blanchard,J.S.
  TITLE     Three-dimensional structure of Escherichia coli dihydrodipicolinate
            reductase in complex with NADH and the inhibitor
            2,6-pyridinedicarboxylate
  JOURNAL   Biochemistry 36 (49), 15081-15088 (1997)
   PUBMED   9398235
REFERENCE   2  (residues 1 to 273)
  AUTHORS   Pavelka,M.S. Jr., Weisbrod,T.R. and Jacobs,W.R. Jr.
  TITLE     Cloning of the dapB gene, encoding dihydrodipicolinate reductase,
            from Mycobacterium tuberculosis
  JOURNAL   J Bacteriol 179 (8), 2777-2782 (1997)
   PUBMED   9098082
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00036.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..273
                     /gene="dapB"
     Protein         1..273
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /EC_number="1.17.1.8"
                     /GO_function="GO:0008839 -
                     4-hydroxy-tetrahydrodipicolinate reductase [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=28667
     Region          5..269
                     /region_name="dapB"
                     /note="4-hydroxy-tetrahydrodipicolinate reductase;
                     TIGR00036"
                     /db_xref="CDD:129147"
ORIGIN      
        1 mhdanirvai agaggrmgrq liqaalaleg vqlgaalere gssllgsdag elagagktgv
       61 tvqssldaik ddfdvfidft rpegtlnhla fcrqhgkgmv igttgfdeag kqairdaaad
      121 iaivfaanfs vgvnvmlkll ekaakvmgdy tdieiieahh rhkvdapsgt alamgeaiah
      181 aldkdlkdca vysreghtge rvpgtigfat vragdivgeh tamfadiger leithkassr
      241 mtfangavrs alwlsgkeng lfdmrdvldl nnl