MULTISPECIES: trifunctional transcriptional regulator/proline

LOCUS       WP_000537528            1320 aa            linear   BCT 10-SEP-2020
            dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase
            [Salmonella].
ACCESSION   WP_000537528
VERSION     WP_000537528.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 1320)
  AUTHORS   Zhang,W., Zhou,Y. and Becker,D.F.
  TITLE     Regulation of PutA-membrane associations by flavin adenine
            dinucleotide reduction
  JOURNAL   Biochemistry 43 (41), 13165-13174 (2004)
   PUBMED   15476410
REFERENCE   2  (residues 1 to 1320)
  AUTHORS   Zhang,M., White,T.A., Schuermann,J.P., Baban,B.A., Becker,D.F. and
            Tanner,J.J.
  TITLE     Structures of the Escherichia coli PutA proline dehydrogenase
            domain in complex with competitive inhibitors
  JOURNAL   Biochemistry 43 (39), 12539-12548 (2004)
   PUBMED   15449943
REFERENCE   3  (residues 1 to 1320)
  AUTHORS   Gu,D., Zhou,Y., Kallhoff,V., Baban,B., Tanner,J.J. and Becker,D.F.
  TITLE     Identification and characterization of the DNA-binding domain of
            the multifunctional PutA flavoenzyme
  JOURNAL   J. Biol. Chem. 279 (30), 31171-31176 (2004)
   PUBMED   15155740
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008772.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11809
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..1320
                     /gene="putA"
     Protein         1..1320
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=143959
     Region          1..1320
                     /region_name="putA"
                     /note="trifunctional transcriptional regulator/proline
                     dehydrogenase/pyrroline-5-carboxylate dehydrogenase;
                     Reviewed; PRK11809"
                     /db_xref="CDD:236989"
ORIGIN      
        1 mgtttmgvkl ddatrerikm aasridrtph wlikqaifsy ldklensdtl pelpalfvga
       61 aneseepvap qdephqpfle faeqilpqsv sraaitaawr rpetdavsml meqarlsppv
      121 aeqahklayq laeklrnqks asgragmvqg llqefslssq egvalmclae allripdkat
      181 rdalirdkis ngnwqshigr spslfvnaat wgllftgrlv sthneanlsr slnriigksg
      241 eplirkgvdm amrlmgeqfv tgetiaqala narkleekgf rysydmlgea altaadaqay
      301 mvsyqqaiha igkasngrgi yegpgisikl salhprysra qydrvmeely prlksltlla
      361 rqydiglnid aeeadrleis ldlleklcfe pelagwngig fviqayqkrc plvidylvdl
      421 asrsrrrlmi rlvkgaywds eikraqmegl egypvytrkv ytdvsylaca kkllavpnli
      481 ypqfathnah tlaaiyhlag qnyypgqyef qclhgmgepl yeqvtgkvad gklnrpcriy
      541 apvgthetll aylvrrllen gantsfvnri adatlpldel vadpveavek laqqegqagi
      601 phpkiplprd lygegrinsa gldlanehrl aslssallsn amqkwqakpv leqpvadgem
      661 tpvinpaepk divgwgreat eseveqalqn avnqapvwfa tppqeraail qraavlmedq
      721 mqqligllvr eagktfsnai aevreavdfl hyyagqvrdd fdnethrplg pvvcispwnf
      781 plaiftgqia aalaagnsvl akpaeqtsli aaqgiaille agvppgvvql lpgrgetvga
      841 qltadarvrg vmftgsteva tllqrniatr ldaqgrpipl iaetggmnam ivdssalteq
      901 vvvdvlasaf dsagqrcsal rvlclqddia ehtlkmlrga maecrmgnpg rlttdigpvi
      961 dseakanier hiqtmrakgr pvfqaarens ddaqewqtgt fvmptliele nfaelekevf
     1021 gpvlhvvryn rnqlaelieq inasgygltl gvhtrideti aqvtgsahvg nlyvnrnmvg
     1081 avvgvqpfgg eglsgtgpka ggplylyrll ahrppnalnt tltrqdaryp vdaqlkttll
     1141 apltaltqwa adrpalqtlc rqfadlaqag tqrllpgptg erntwtllpr ervlcladde
     1201 qdaltqlaav lavgsqalws ddafhrdlak rlpaavaarv qfakaetlma qpfdavifhg
     1261 dsdklrtvce avaaregaiv svqgfarges nillerlyie rslsvntaaa ggnaslmtig