MULTISPECIES: HNH endonuclease [Salmonella].

LOCUS       WP_000536990             280 aa            linear   BCT 20-FEB-2025
ACCESSION   WP_000536990
VERSION     WP_000536990.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 280)
  AUTHORS   Nemeth,E., Kozisek,M., Schilli,G.K. and Gyurcsik,B.
  TITLE     Preorganization of the catalytic Zn(2+)-binding site in the HNH
            nuclease motif--A solution study
  JOURNAL   J Inorg Biochem 151, 143-149 (2015)
   PUBMED   25898772
REFERENCE   2  (residues 1 to 280)
  AUTHORS   Veluchamy,A., Mary,S., Acharya,V., Mehta,P., Deva,T. and
            Krishnaswamy,S.
  TITLE     HNHDb: a database on pattern based classification of HNH domains
            reveals functional relevance of sequence patterns and domain
            associations
  JOURNAL   Bioinformation 4 (2), 80-83 (2009)
   PUBMED   20198175
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 280)
  AUTHORS   Mehta,P., Katta,K. and Krishnaswamy,S.
  TITLE     HNH family subclassification leads to identification of commonality
            in the His-Me endonuclease superfamily
  JOURNAL   Protein Sci 13 (1), 295-300 (2004)
   PUBMED   14691243
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11459846
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..280
                     /product="HNH endonuclease"
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=32541
     Region          173..276
                     /region_name="COG3183"
                     /note="Predicted restriction endonuclease, HNH family
                     [Defense mechanisms]"
                     /db_xref="CDD:442416"
ORIGIN      
        1 mgtlkliqyp sqllsltisd iinkqnlsql iqkskkddse nwegkdwiik ntpqqginwi
       61 gehpnikavi iktkdgsyad dgwknnekti ysysfkaakg iinfndsanr vlinqpisny
      121 pillftdssn kwefqgcfki idilekavil ekmisfpsln dknsdnddvi lyknehtegk
      181 ikyithmlse rnrkiideik dnsqwvcdic eikfldkygk nyieahhkip ihtftgehri
      241 lktdfallcp nchkavhiyl reenlqyeea kikirnilkr