tyrosine-type recombinase/integrase [Escherichia coli].

LOCUS       WP_000533600             340 aa            linear   BCT 25-AUG-2024
ACCESSION   WP_000533600
VERSION     WP_000533600.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 340)
  AUTHORS   Guo,F., Gopaul,D.N. and van Duyne,G.D.
  TITLE     Structure of Cre recombinase complexed with DNA in a site-specific
            recombination synapse
  JOURNAL   Nature 389 (6646), 40-46 (1997)
   PUBMED   9288963
REFERENCE   2  (residues 1 to 340)
  AUTHORS   Kwon,H.J., Tirumalai,R., Landy,A. and Ellenberger,T.
  TITLE     Flexibility in DNA recombination: structure of the lambda integrase
            catalytic core
  JOURNAL   Science 276 (5309), 126-131 (1997)
   PUBMED   9082984
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012798.5
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00589.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..340
                     /product="tyrosine-type recombinase/integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=39014
     Region          78..>222
                     /region_name="DNA_BRE_C"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain; cl00213"
                     /db_xref="CDD:469662"
     Region          169..321
                     /region_name="DNA_BRE_C"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain; cl00213"
                     /db_xref="CDD:469662"
     Site            order(180,194..195,259,261,284,316)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:271175"
     Site            order(194,284,287,307,316)
                     /site_type="active"
                     /db_xref="CDD:271175"
ORIGIN      
        1 mgrrrknpeh eklppkvypn kysvwkptsr esvtltaied glaalwkkye etvnhrdram
       61 tfgrlwekfl asayyselsp rtqkdylqhq kkllavfgkv ladsvkpehi rrymdkrgeq
      121 sktqanheks smsrvyswgy ergyvkanpc agvskfkakn reryvtdkey qavlsvaplp
      181 vfiameiayl caarvsdvls lkweqigndg ifiqqgktgk kqikawsprl qaaiekakql
      241 ptsayvisnq ygnrymykgf nemwvearnh agkisgiltd ftfhdlkakg isdyegssrd
      301 kqlfsghkte gqvliydrkv kvsptldvpl peniprkysk