NADH-dependent methylglyoxal reductase [Shigella flexneri].

LOCUS       WP_000522808             311 aa            linear   BCT 10-JUL-2019
ACCESSION   WP_000522808
VERSION     WP_000522808.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 311)
  AUTHORS   Vogel-Scheel,J., Alpert,C., Engst,W., Loh,G. and Blaut,M.
  TITLE     Requirement of purine and pyrimidine synthesis for colonization of
            the mouse intestine by Escherichia coli
  JOURNAL   Appl. Environ. Microbiol. 76 (15), 5181-5187 (2010)
   PUBMED   20562286
REFERENCE   2  (residues 1 to 311)
  AUTHORS   Di Luccio,E., Elling,R.A. and Wilson,D.K.
  TITLE     Identification of a novel NADH-specific aldo-keto reductase using
            sequence and structural homologies
  JOURNAL   Biochem. J. 400 (1), 105-114 (2006)
   PUBMED   16813561
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008161
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..311
                     /gene="ydjG"
     Protein         1..311
                     /product="NADH-dependent methylglyoxal reductase"
                     /EC_number="1.1.1.-"
                     /calculated_mol_wt=34600
     Region          1..304
                     /region_name="AKR_AKR11B2"
                     /note="Escherichia coli NADH-specific methylglyoxal
                     reductase (YdjG) and similar proteins; cd19149"
                     /db_xref="CDD:381375"
     Site            order(4..6,39,44,70,154..155,174,202..208,211,213,224,257,
                     274..276,278,282)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:381375"
     Site            order(39,44,70,121)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381375"
ORIGIN      
        1 mglgtwaigg gpawngdldr qicidtilea hrcginlidt algynfgnse vivgqalkkl
       61 preqvvvetk cgivwerkgs lfnkvgdrql yknlspesir eeveaslqrl gidyidiymt
      121 hwqsvppfft piaetvavln elkaegkira igaanvdadh ireylqygel diiqakysil
      181 dramenellp lcrdngivvq vyspleqgll tgtitrdyvp ggarankvwf qrenmlkvid
      241 mleqwqplca ryqctiptla lawilkqsdl isilsgatap eqvrenvaal ninlsdadat
      301 lmremaeale r