MULTISPECIES: nucleoside permease [Salmonella].

LOCUS       WP_000513241             418 aa            linear   BCT 26-JUL-2024
ACCESSION   WP_000513241
VERSION     WP_000513241.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 418)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 418)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 418)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   4  (residues 1 to 418)
  AUTHORS   Law,C.J., Maloney,P.C. and Wang,D.N.
  TITLE     Ins and outs of major facilitator superfamily antiporters
  JOURNAL   Annu Rev Microbiol 62, 289-305 (2008)
   PUBMED   18537473
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10017491
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..418
                     /product="nucleoside permease"
                     /GO_function="GO:0015506 - nucleoside:proton symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015858 - nucleoside transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=45837
     Region          1..418
                     /region_name="2A0110"
                     /note="nucleoside transporter; TIGR00889"
                     /db_xref="CDD:129967"
     Site            order(14..15,18..19,22,55,106..107,109..111,114,136,
                     139..140,143,217,220..221,224..226,229,264,268,321..322,
                     326,330,346,349..350,353..354,357)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340866"
ORIGIN      
        1 mgitsrlkvm sflqyfiwgs wlvtlgsymi ntldftganv gmvysskgla aiimpgimgi
       61 iadkwlraer aymlchlvca gallyattvt dpqtmfwvml vnamaympti alsnsvsysc
      121 lakagqdpvt sfppvrvfgt igfivamwtv slmglelssa qlyiasgasl llalyaltlp
      181 kipvaekkan ttlasklgld afvlfknprm aifflfamml gavlqitnvf gnpflhdfar
      241 npefadsfvv kypsillsvs qmaevgfilt ipfflkrfgi ktvmlmsmla wtlrfgffaf
      301 gdpspfgfvl lllsmivygc afdffnisgs vfveqevdss irasaqglfm tmvngvgawi
      361 gsllsgmavd yfsidgvkdw qtiwlvfaay alalavifal ffkyqhhpek lstkslah