shikimate kinase AroK [Escherichia coli].

LOCUS       WP_000502618             225 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_000502618
VERSION     WP_000502618.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 225)
  AUTHORS   Krell,T., Coyle,J.E., Horsburgh,M.J., Coggins,J.R. and
            Lapthorn,A.J.
  TITLE     Crystallization and preliminary X-ray crystallographic analysis of
            shikimate kinase from Erwinia chrysanthemi
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 53 (Pt 5), 612-614 (1997)
   PUBMED   15299895
REFERENCE   2  (residues 1 to 225)
  AUTHORS   Lobner-Olesen,A. and Marinus,M.G.
  TITLE     Identification of the gene (aroK) encoding shikimic acid kinase I
            of Escherichia coli
  JOURNAL   J. Bacteriol. 174 (2), 525-529 (1992)
   PUBMED   1309529
REFERENCE   3  (residues 1 to 225)
  AUTHORS   Millar,G., Lewendon,A., Hunter,M.G. and Coggins,J.R.
  TITLE     The cloning and expression of the aroL gene from Escherichia coli
            K12. Purification and complete amino acid sequence of shikimate
            kinase II, the aroL-gene product
  JOURNAL   Biochem. J. 237 (2), 427-437 (1986)
   PUBMED   3026317
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003456.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05057
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..225
                     /gene="aroK"
     Protein         1..225
                     /product="shikimate kinase AroK"
                     /EC_number="2.7.1.71"
                     /calculated_mol_wt=25097
     Region          53..225
                     /region_name="aroK"
                     /note="shikimate kinase AroK; PRK05057"
                     /db_xref="CDD:235335"
     Site            order(66..71,165,172)
                     /site_type="other"
                     /note="ADP binding site [chemical binding]"
                     /db_xref="CDD:238260"
     Site            order(70,86,88)
                     /site_type="other"
                     /note="magnesium binding site [ion binding]"
                     /db_xref="CDD:238260"
     Site            order(88,112,115,133..135,192)
                     /site_type="active"
                     /note="putative shikimate binding site [active]"
                     /db_xref="CDD:238260"
ORIGIN      
        1 mgdlfscqtr wsieiifslt laisyevsvh vlrsslseag lsltnslsst ekmaekrnif
       61 lvgpmgagks tigrqlaqql nmefydsdqe iekrtgadvg wvfdlegeeg frdreekvin
      121 eltekqgivl atgggsvksr etrnrlsarg vvvylettie kqlartqrdk krpllhvetp
      181 prevlealan ernplyeeia dvtirtddqs akvvanqiih mlesn