7-alpha-hydroxysteroid dehydrogenase [Shigella flexneri].

LOCUS       WP_000483342             206 aa            linear   BCT 24-OCT-2020
ACCESSION   WP_000483342
VERSION     WP_000483342.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004773.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK06113
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..206
                     /gene="hdhA"
     Protein         1..206
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /EC_number="1.1.1.159"
                     /calculated_mol_wt=21534
     Region          1..205
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(18,20..21,23,42..44,95..97,144..146,159,163,
                     189..192)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187535"
     Site            order(118,146,159,163)
                     /site_type="active"
                     /db_xref="CDD:187535"
ORIGIN      
        1 mfnsdnlrld gkcaiitgag agigkeiait fatagasvvv sdinadaanh vvdeiqqldg
       61 qafawrcdit seqelsalad favsnlgkvd ilvnnagggg pkpfdmpmad frrayelnvf
      121 sffhlsqlva pemekngggv iltitsmaae nkninmtsya sskaaashlv rnmafdlgek
      181 nirvnsiapg ailtdalksv itpeig