MULTISPECIES: SPI-1 type III secretion system effector E3 ubiquitin

LOCUS       WP_000482001             765 aa            linear   BCT 10-SEP-2020
            transferase SlrP [Salmonella].
ACCESSION   WP_000482001
VERSION     WP_000482001.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 765)
  AUTHORS   Bernal-Bayard,J. and Ramos-Morales,F.
  TITLE     Salmonella type III secretion effector SlrP is an E3 ubiquitin
            ligase for mammalian thioredoxin
  JOURNAL   J. Biol. Chem. 284 (40), 27587-27595 (2009)
   PUBMED   19690162
REFERENCE   2  (residues 1 to 765)
  AUTHORS   Haraga,A. and Miller,S.I.
  TITLE     A Salmonella enterica serovar typhimurium translocated leucine-rich
            repeat effector protein inhibits NF-kappa B-dependent gene
            expression
  JOURNAL   Infect. Immun. 71 (7), 4052-4058 (2003)
   PUBMED   12819095
REFERENCE   3  (residues 1 to 765)
  AUTHORS   Miao,E.A. and Miller,S.I.
  TITLE     A conserved amino acid sequence directing intracellular type III
            secretion by Salmonella typhimurium
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 97 (13), 7539-7544 (2000)
   PUBMED   10861017
REFERENCE   4  (residues 1 to 765)
  AUTHORS   Tsolis,R.M., Townsend,S.M., Miao,E.A., Miller,S.I., Ficht,T.A.,
            Adams,L.G. and Baumler,A.J.
  TITLE     Identification of a putative Salmonella enterica serotype
            typhimurium host range factor with homology to IpaH and YopM by
            signature-tagged mutagenesis
  JOURNAL   Infect. Immun. 67 (12), 6385-6393 (1999)
   PUBMED   10569754
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000643
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..765
                     /gene="slrP"
     Protein         1..765
                     /product="SPI-1 type III secretion system effector E3
                     ubiquitin transferase SlrP"
                     /calculated_mol_wt=86741
     Region          1..764
                     /region_name="PRK15370"
                     /note="type III secretion system effector E3 ubiquitin
                     transferase SlrP"
                     /db_xref="CDD:185268"
     Region          181..200
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          201..221
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          222..242
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          243..263
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          264..284
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          285..306
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          308..329
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          348..368
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
ORIGIN      
        1 mfnitniqst arhqsisnea stevplkeei wnkisaffss ehqveaqnci aylchppeta
       61 speeikskfe clrmlafpay adniqysrgg adqycilsen sqeilsivfn tegytveggg
      121 ksvtytrvte seqassasgs kdavnyeliw sewvkeapak eaanreeavq rmrdclknnk
      181 telrlkilgl ttipayipeq ittlildnne lkslpenlqg niktlyansn qltsipatlp
      241 dtiqemelsi nritelperl psalqsldlf hnkisclpen lpeelrylsv ydnsirtlpa
      301 hlpsgithln vqsnsltalp etlppglktl eagenaltsl paslppelqv ldvsknqitv
      361 lpetlpptit tldvsrnalt nlpenlpaal qimqasrnnl vrlpeslphf rgegpqptri
      421 iveynpfser tiqnmqrlms svdyqgprvl famgdfsivr vtrplhqavq gwltsleeed
      481 vnqwrafeae anaaafsgfl dylgdtqntr hpdfkeqvsa wlmrlaedsa lretvfiiam
      541 natiscedrv tlayhqmqea tlvhdaerga fdshlaelim agreifrleq ieslarekvk
      601 rlffidevev flgfqnqlre slslttmtrd mrfynvsgit esdldeaeir ikmaenrdfh
      661 kwfalwgpwh kvleriapee wremmakrde cietdeyqsr vnaeledlri addsdaertt
      721 evqmdaerai gikimeeinq tlfteimeni llkkevsslm saywr