Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

BlaEC family class C beta-lactamase [Escherichia coli].


LOCUS       WP_000477369             377 aa            linear   BCT 01-APR-2024
ACCESSION   WP_000477369
VERSION     WP_000477369.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 377)
  AUTHORS   Mammeri,H., Poirel,L., Fortineau,N. and Nordmann,P.
  TITLE     Naturally occurring extended-spectrum cephalosporinases in
            Escherichia coli
  JOURNAL   Antimicrob Agents Chemother 50 (7), 2573-2576 (2006)
   PUBMED   16801449
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000185.2
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..377
                     /product="BlaEC family class C beta-lactamase"
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=41401
     Region          1..377
                     /region_name="ampC"
                     /note="beta-lactamase/D-alanine carboxypeptidase;
                     Provisional; PRK11289"
                     /db_xref="CDD:236894"
ORIGIN      
        1 mfkttlcall itascstfaa pqqindivhr titplieqqk ipgmavaviy qgkpyyftwg
       61 yadiakkqpv tqqtlfelgs vsktftgvlg gdaiargeik lsdpatkywp eltakqwngi
      121 tllhlatyta gglplqvpde vksssdllrf yqnwqpawap gtqrlyanss iglfgalavk
      181 psglsfeqam qtrvfqplkl nhtwinvppa eeknyawgyr egkavhvspg aldaetygvk
      241 stiedmacwv rsnmnprdin dktlqqgiql aqsrywqtgd myqglgweml dwpvnpdiiv
      301 ngsdnkiala arpvkaitpp tpavraswvh ktgatggfgs yvafipekel givmlankny
      361 pnparvaaaw qilnalq