MULTISPECIES: tagatose bisphosphate family class II aldolase

LOCUS       WP_000469985             284 aa            linear   BCT 03-JUN-2024
            [Enterobacteriaceae].
ACCESSION   WP_000469985
VERSION     WP_000469985.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 284)
  AUTHORS   Hall,D.R., Bond,C.S., Leonard,G.A., Watt,C.I., Berry,A. and
            Hunter,W.N.
  TITLE     Structure of tagatose-1,6-bisphosphate aldolase. Insight into
            chiral discrimination, mechanism, and specificity of class II
            aldolases
  JOURNAL   J Biol Chem 277 (24), 22018-22024 (2002)
   PUBMED   11940603
REFERENCE   2  (residues 1 to 284)
  AUTHORS   Zgiby,S.M., Thomson,G.J., Qamar,S. and Berry,A.
  TITLE     Exploring substrate binding and discrimination in fructose1,
            6-bisphosphate and tagatose 1,6-bisphosphate aldolases
  JOURNAL   Eur J Biochem 267 (6), 1858-1868 (2000)
   PUBMED   10712619
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01858.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..284
                     /product="tagatose bisphosphate family class II aldolase"
                     /EC_number="4.1.2.40"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=30791
     Region          1..284
                     /region_name="gatY"
                     /note="tagatose-bisphosphate aldolase subunit GatY;
                     PRK12737"
                     /db_xref="CDD:183710"
     Site            order(27..29,32,52,55..57,61,65,68..69,142,233..234,
                     236..237,240,244,247)
                     /site_type="other"
                     /note="intersubunit interface [polypeptide binding]"
                     /db_xref="CDD:238477"
     Site            order(82..83,179..181,183,208..209,211,230,232..233)
                     /site_type="active"
                     /db_xref="CDD:238477"
     Site            order(83,180,208)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:238477"
     Site            order(179,181,183,209,211)
                     /site_type="other"
                     /note="Na+ binding site [ion binding]"
                     /db_xref="CDD:238477"
ORIGIN      
        1 mfiissknml qkaqhagyav pafnihnlet lqvvvetaae mrsplivagt pgtfsyagmg
       61 nivaiagdla reynlplaih ldhhesladi eskvmagirs vmidgshfpf eenvalvksv
      121 vdfchrydts veaelgrlgg ieddlvvdsk dalytnpqqa refvartgid slavaigtah
      181 gmyaaepkld ferlaeiral vdiplvlhga sglpesdirq aislgvckvn vatelkiafs
      241 dalkeyflqn pkandprhym qpakqamkev vrkvihvcgc egql