DNA polymerase V catalytic protein [Escherichia coli].

LOCUS       WP_000457644             422 aa            linear   BCT 11-FEB-2021
ACCESSION   WP_000457644
VERSION     WP_000457644.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 422)
  AUTHORS   Erdem,A.L., Jaszczur,M., Bertram,J.G., Woodgate,R., Cox,M.M. and
            Goodman,M.F.
  TITLE     DNA polymerase V activity is autoregulated by a novel intrinsic
            DNA-dependent ATPase
  JOURNAL   Elife 3, e02384 (2014)
   PUBMED   24843026
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 422)
  AUTHORS   Tang,M., Pham,P., Shen,X., Taylor,J.S., O'Donnell,M., Woodgate,R.
            and Goodman,M.F.
  TITLE     Roles of E. coli DNA polymerases IV and V in lesion-targeted and
            untargeted SOS mutagenesis
  JOURNAL   Nature 404 (6781), 1014-1018 (2000)
   PUBMED   10801133
REFERENCE   3  (residues 1 to 422)
  AUTHORS   Reuven,N.B., Arad,G., Maor-Shoshani,A. and Livneh,Z.
  TITLE     The mutagenesis protein UmuC is a DNA polymerase activated by
            UmuD', RecA, and SSB and is specialized for translesion replication
  JOURNAL   J Biol Chem 274 (45), 31763-31766 (1999)
   PUBMED   10542196
REFERENCE   4  (residues 1 to 422)
  AUTHORS   Bruck,I., Woodgate,R., McEntee,K. and Goodman,M.F.
  TITLE     Purification of a soluble UmuD'C complex from Escherichia coli.
            Cooperative binding of UmuD'C to single-stranded DNA
  JOURNAL   J Biol Chem 271 (18), 10767-10774 (1996)
   PUBMED   8631887
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011302
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..422
                     /gene="umuC"
     Protein         1..422
                     /product="DNA polymerase V catalytic protein"
                     /EC_number="2.7.7.7"
                     /calculated_mol_wt=47537
     Region          1..422
                     /region_name="umuC"
                     /note="translesion error-prone DNA polymerase V subunit
                     UmuC; PRK03609"
                     /db_xref="CDD:179607"
     Site            order(6..7,10..11,42,45,101..102,154)
                     /site_type="active"
                     /db_xref="CDD:176454"
     Site            order(99,102,185..191,220,245..250,277,296..300,302)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:176454"
ORIGIN      
        1 mfalcdvnaf yascetvfrp elwgkpvvvl snndgcviar naeakalgvk mgdpwfkqkd
       61 lfrrcgvvcf ssnyelyadm snrvmstlee lsprveiysi deafcdltgv rncrdltdfg
      121 reiratvlqr thltvgvgia qtktlaklan haakkwqrqt ggvvdlsnle rqrklmsalp
      181 vddvwgigrr iskkldamgi ktvldladtd irfirkhfnv vlertvrelr gepclqleef
      241 aptkqeiics rsfgeritdy tsmrqaicsy aaraaeklrs ehqycrfist fiktspfaln
      301 epyygnsasv klltptqdsr diinaatrsl daiwqaghry qkagvmlgdf fsqgvaqlnl
      361 fddnaprpgs eqlmavmdtl nakegrgtly fagqgiqqqw qmkramlspr yttrssdllr
      421 vk