MULTISPECIES: lipid A hydroxylase LpxO [Salmonella].

LOCUS       WP_000457024             302 aa            linear   BCT 10-SEP-2020
ACCESSION   WP_000457024
VERSION     WP_000457024.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 302)
  AUTHORS   Llobet,E., Martinez-Moliner,V., Moranta,D., Dahlstrom,K.M.,
            Regueiro,V., Tomas,A., Cano,V., Perez-Gutierrez,C., Frank,C.G.,
            Fernandez-Carrasco,H., Insua,J.L., Salminen,T.A., Garmendia,J. and
            Bengoechea,J.A.
  TITLE     Deciphering tissue-induced Klebsiella pneumoniae lipid A structure
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 112 (46), E6369-E6378 (2015)
   PUBMED   26578797
REFERENCE   2  (residues 1 to 302)
  AUTHORS   MacArthur,I., Jones,J.W., Goodlett,D.R., Ernst,R.K. and Preston,A.
  TITLE     Role of pagL and lpxO in Bordetella bronchiseptica lipid A
            biosynthesis
  JOURNAL   J. Bacteriol. 193 (18), 4726-4735 (2011)
   PUBMED   21764941
REFERENCE   3  (residues 1 to 302)
  AUTHORS   Moskowitz,S.M. and Ernst,R.K.
  TITLE     The role of Pseudomonas lipopolysaccharide in cystic fibrosis
            airway infection
  JOURNAL   Subcell. Biochem. 53, 241-253 (2010)
   PUBMED   20593270
REFERENCE   4  (residues 1 to 302)
  AUTHORS   Gibbons,H.S., Reynolds,C.M., Guan,Z. and Raetz,C.R.
  TITLE     An inner membrane dioxygenase that generates the 2-hydroxymyristate
            moiety of Salmonella lipid A
  JOURNAL   Biochemistry 47 (9), 2814-2825 (2008)
   PUBMED   18254598
REFERENCE   5  (residues 1 to 302)
  AUTHORS   Gibbons,H.S., Lin,S., Cotter,R.J. and Raetz,C.R.
  TITLE     Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate
            moiety in Salmonella typhimurium lipid A. Function of LpxO, A new
            Fe2+/alpha-ketoglutarate-dependent dioxygenase homologue
  JOURNAL   J. Biol. Chem. 275 (42), 32940-32949 (2000)
   PUBMED   10903325
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF033391.2
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..302
                     /gene="lpxO"
     Protein         1..302
                     /product="lipid A hydroxylase LpxO"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /calculated_mol_wt=34723
     Region          16..288
                     /region_name="Asp_Arg_Hydrox"
                     /note="Aspartyl/Asparaginyl beta-hydroxylase; cl42444"
                     /db_xref="CDD:478204"
ORIGIN      
        1 mfaaiiigif iisviyahsr gvekqklsrq lfdhstfmap inmfmtrfst lpakqpyfdt
       61 tafpelqklt enwqvireea lqlqhhikaa qanndagfnt ffkrgwkrfy lkwysdahps
      121 aetlcpittk lvnsipsika amfaelppga ylgkhrdpya gsvryhlgls tpnddrcfie
      181 vdrqrhswrd gkavifdety vhwaenkteq triilfcdie rpmkwrwaqs vnhwvgaslm
      241 saasspnden drtgainrif kyvhaardag qrlkkknrtl yyalkylvia aifaaiilfs
      301 ll