MULTISPECIES: aldo/keto reductase [Salmonella].

FASTA View on NCBI
LOCUS       WP_000456774             289 aa            linear   BCT 25-JUL-2024
ACCESSION   WP_000456774
VERSION     WP_000456774.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 289)
  AUTHORS   Hyndman,D., Bauman,D.R., Heredia,V.V. and Penning,T.M.
  TITLE     The aldo-keto reductase superfamily homepage
  JOURNAL   Chem Biol Interact 143-144, 621-631 (2003)
   PUBMED   12604248
REFERENCE   2  (residues 1 to 289)
  AUTHORS   Jez,J.M., Bennett,M.J., Schlegel,B.P., Lewis,M. and Penning,T.M.
  TITLE     Comparative anatomy of the aldo-keto reductase superfamily
  JOURNAL   Biochem J 326 (Pt 3) (Pt 3), 625-636 (1997)
   PUBMED   9307009
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 14442695
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..289
                     /product="aldo/keto reductase"
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=32276
     Region          5..263
                     /region_name="AKR_AKR5F1"
                     /note="the AKR5F family of aldo-keto reductase (AKR);
                     cd19133"
                     /db_xref="CDD:381359"
     Site            order(18..20,44,48..49,78,112..113,140..141,162,188..194,
                     204,216,231..236,239,242..243)
                     /site_type="active"
                     /db_xref="CDD:381359"
     Site            order(44,49,78,112)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381359"
ORIGIN      
        1 meysilsnnl kmpmvgfgvf kvtdkeecqq svlsairsgy rlidtaavyg nedavgdavr
       61 eaiatglctr eelfitsklw vqdmanydla kagieaslkk sgldyfdlyl lhqamgdyfs
      121 awraledaye agklkaigvs nfyahvlanf cetvritpmv nqvelhpyfa qpaaletmkh
      181 ynvqpeawap lgggrhkpye nvmlqgiada hqktiaqvvl rwnvqrgvtv ipkstrqeri
      241 eenfaiwdfs ltdnemaqin aldlgyvgea vkhfnpefvr gclgvkihd