Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

peptide chain release factor N(5)-glutamine methyltransferase


LOCUS       WP_000456466             277 aa            linear   BCT 27-DEC-2023
            [Escherichia coli].
ACCESSION   WP_000456466
VERSION     WP_000456466.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 277)
  AUTHORS   Selengut,J.D., Rusch,D.B. and Haft,D.H.
  TITLE     Sites Inferred by Metabolic Background Assertion Labeling (SIMBAL):
            adapting the Partial Phylogenetic Profiling algorithm to scan
            sequences for signatures that predict protein function
  JOURNAL   BMC Bioinformatics 11, 52 (2010)
   PUBMED   20102603
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 277)
  AUTHORS   Heurgue-Hamard,V., Champ,S., Engstrom,A., Ehrenberg,M. and
            Buckingham,R.H.
  TITLE     The hemK gene in Escherichia coli encodes the N(5)-glutamine
            methyltransferase that modifies peptide release factors
  JOURNAL   EMBO J 21 (4), 769-778 (2002)
   PUBMED   11847124
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03534.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..277
                     /gene="prmC"
     Protein         1..277
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /EC_number="2.1.1.297"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /calculated_mol_wt=30885
     Region          1..277
                     /region_name="hemK_fam"
                     /note="HemK family putative methylases; TIGR00536"
                     /db_xref="CDD:273125"
ORIGIN      
        1 meyqhwlrea isqlqasesp rrdaeilleh vtgrgrtfil afgetqltde qcqqldallt
       61 rrrdgepiah ltgvrefwsl plfvspatli prpdteclve qalarlpeqp crildlgtgt
      121 gaialalare rpdceitavd rmpdavalaq rnaqhlaikn ihilqsdwfs alagqqfami
      181 vsnppyideq dphlqqgdvr fepltalvaa dsgmadivhi ieqsrnalvs ggflllehgw
      241 qqgeavrqaf ilagyhdvet crdygdnerv tlgryyq