MULTISPECIES: malonate-semialdehyde dehydrogenase IolA

LOCUS       WP_000450731             501 aa            linear   BCT 14-APR-2021
            [Salmonella].
ACCESSION   WP_000450731
VERSION     WP_000450731.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 501)
  AUTHORS   Kroger,C. and Fuchs,T.M.
  TITLE     Characterization of the myo-inositol utilization island of
            Salmonella enterica serovar Typhimurium
  JOURNAL   J. Bacteriol. 191 (2), 545-554 (2009)
   PUBMED   19011032
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to
            AAL23241.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006483
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..501
                     /gene="iolA"
     Protein         1..501
                     /product="malonate-semialdehyde dehydrogenase IolA"
                     /calculated_mol_wt=53587
     Region          4..485
                     /region_name="ALDH_F6_MMSDH"
                     /note="Methylmalonate semialdehyde dehydrogenase and ALDH
                     family members 6A1 and 6B2; cd07085"
                     /db_xref="CDD:143404"
     Site            order(61,63,67,70,74,107,110..111,120..127,132,135,138,
                     231,235,238,241,243,421,423..424,426..427,430,433..434,
                     436,438..441,450,454,456,470,477..482,484..485)
                     /site_type="other"
                     /note="tetrameric interface [polypeptide binding]"
                     /db_xref="CDD:143404"
     Site            order(147..150,158,173,176,206,223..226,229,247..249,281,
                     386,388,414)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:143404"
     Site            order(150,247,278,281)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143404"
ORIGIN      
        1 metvgnfihg kttlsssget lpvtnpatgk virqvtqstr eemlaaiqsa heafpawskm
       61 tplrrarilf efkvllekhr delaalivse hgkvwsdalg eltrgievve facgiphlsk
      121 geysfnvgsg vdsfslmqpl gvvagitpfn fpamvpmwmf pvalacgntf vlkppalvps
      181 aslrmaqllq easlpdgvfn vvhcgneaas lltsdprvqa vsfvgssava ehiyttasah
      241 gkrvqafgaa knhaivmpda dldatvnaim ggafgsager cmalpvvvav gdetadrlie
      301 rlkpliaalr igpgelrgkd enemgpvvsr ahqqkvlgyi dkgvsegatl vmdgrnysva
      361 gypegfyvgg tlfdnvtpem tiwreeifgp vlgivrvpdy ataistvnsh efgngsvift
      421 tnghyarefa qsveagmvgi nipvpvpmaf hsfggwkrsv fgalnvhgpd gvrfytrmkt
      481 vtsrwpngqq ivsefsmptl g