lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase [Escherichia coli].

LOCUS       WP_000448391             323 aa            linear   BCT 17-JUN-2024
ACCESSION   WP_000448391
VERSION     WP_000448391.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02208.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..323
                     /gene="lpxM"
                     /gene_synonym="msbB"
     Protein         1..323
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /EC_number="2.3.1.243"
                     /GO_component="GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /GO_process="GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species.; LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species."
                     /calculated_mol_wt=37245
     Region          1..321
                     /region_name="PRK08943"
                     /note="lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA
                     acyltransferase; Validated"
                     /db_xref="CDD:236355"
     Site            order(139,142,144,161..164,210..212)
                     /site_type="active"
                     /note="putative acyl-acceptor binding pocket [active]"
                     /db_xref="CDD:153246"
ORIGIN      
        1 metkknnsey ipefdksfrh prywgawlgv aamagialtp pkfrdpilar lgriagrlgk
       61 ssrrralinl slcfpersea ereaivdemf atapqamamm aelairgpek iqprvdwqgl
      121 eiieemrrnn ekviflvphg wavdipamlm asqgqkmaam fhnqgnpvfd yvwntvrrrf
      181 ggrlharndg ikpfiqsvrq gywgyylpdq dhgpehsefv dffatykatl paigrlmkvc
      241 rarvvplfpi ydgkthrlti qvrppmddll eaddhtiarr mneeveifvg prpeqytwil
      301 kllktrkpge iqpykrkdly pik