PDDEXK nuclease domain-containing protein [Escherichia coli].

LOCUS       WP_000445155             349 aa            linear   BCT 20-JAN-2025
ACCESSION   WP_000445155
VERSION     WP_000445155.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 349)
  AUTHORS   Kosinski,J., Feder,M. and Bujnicki,J.M.
  TITLE     The PD-(D/E)XK superfamily revisited: identification of new members
            among proteins involved in DNA metabolism and functional
            predictions for domains of (hitherto) unknown function
  JOURNAL   BMC Bioinformatics 6, 172 (2005)
   PUBMED   16011798
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10008845
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..349
                     /product="PDDEXK nuclease domain-containing protein"
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /calculated_mol_wt=40567
     Region          1..344
                     /region_name="YhcG"
                     /note="Predicted nuclease of restriction endonuclease-like
                     (RecB) superfamily, DUF1016 family [General function
                     prediction only]; COG4804"
                     /db_xref="CDD:443832"
ORIGIN      
        1 meslsertst gyqqihdgii hlvdsartet vrsvnalmta tyweigrriv efeqggeara
       61 aygaqlikrl skdlslrykr gfsaknlrqm rlfylffqhv eirqtvsgel tplpwstyvr
      121 llsvknadtr sfyeketlrc gwsvrqlerq iatqfyertl lshdksamlq qhapaethil
      181 pqqairdpfv leflelkdey sesdfeeali nhlmdfmlel gddfafvgrq rrlriddnwf
      241 rvdllffhrr lrcllivdlk vgkfsysdag qmnmylnyak ehwtlpdenp piglvlcaek
      301 gvgeahyala glpntvlase ykmqlpdekr ladelvrtqa vleegyrlr