NADP-dependent isocitrate dehydrogenase [Escherichia coli].

LOCUS       WP_000444477             416 aa            linear   BCT 18-JAN-2020
ACCESSION   WP_000444477
VERSION     WP_000444477.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005425.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK07006
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..416
                     /gene="icd"
     Protein         1..416
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004450 - isocitrate dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /calculated_mol_wt=45640
     Region          8..416
                     /region_name="PRK07006"
                     /note="isocitrate dehydrogenase; Reviewed"
                     /db_xref="CDD:180792"
ORIGIN      
        1 meskvvvpaq gkkitlqngk lnvpenpiip yiegdgigvd vtpamlkvvd aavekaykge
       61 rkiswmeiyt gekstqvygq dvwlpaetld lireyrvaik gplttpvggg irslnvalrq
      121 eldlyiclrp vryyqgtpsp vkhpeltdmv ifrensediy agiewkadsa daekvikflr
      181 eemgvkkirf pehcgigikp cseegtkrlv raaieyaian drdsvtlvhk gnimkftega
      241 fkdwgyelar eefggelidg gpwlkvknpn tgkeivikdv iadaflqqil lrpaeydvia
      301 cmnlngdyis dalaaqvggi giapganigd ecalfeathg tapkyagqdk vnpgsiilsa
      361 emmlrhmgwt eaadlivkgm egainaktvt ydferlmega kllkcsefgd aiiknm