MULTISPECIES: 5-methylcytosine-specific restriction endonuclease

LOCUS       WP_000443951             459 aa            linear   BCT 31-MAR-2024
            subunit McrB [Escherichia].
ACCESSION   WP_000443951
VERSION     WP_000443951.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 459)
  AUTHORS   Kruger,T., Wild,C. and Noyer-Weidner,M.
  TITLE     McrB: a prokaryotic protein specifically recognizing DNA containing
            modified cytosine residues
  JOURNAL   EMBO J 14 (11), 2661-2669 (1995)
   PUBMED   7781618
REFERENCE   2  (residues 1 to 459)
  AUTHORS   Dila,D., Sutherland,E., Moran,L., Slatko,B. and Raleigh,E.A.
  TITLE     Genetic and sequence organization of the mcrBC locus of Escherichia
            coli K-12
  JOURNAL   J Bacteriol 172 (9), 4888-4900 (1990)
   PUBMED   2203735
REFERENCE   3  (residues 1 to 459)
  AUTHORS   Ross,T.K., Achberger,E.C. and Braymer,H.D.
  TITLE     Nucleotide sequence of the McrB region of Escherichia coli K-12 and
            evidence for two independent translational initiation sites at the
            mcrB locus
  JOURNAL   J Bacteriol 171 (4), 1974-1981 (1989)
   PUBMED   2649480
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to P15005.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011028
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..459
                     /gene="mcrB"
     Protein         1..459
                     /product="5-methylcytosine-specific restriction
                     endonuclease subunit McrB"
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /calculated_mol_wt=53026
     Region          1..459
                     /region_name="PRK11331"
                     /note="5-methylcytosine-specific restriction enzyme
                     subunit McrB; Provisional"
                     /db_xref="CDD:183088"
ORIGIN      
        1 mesiqpwiek fikqaqqqrs qstkdyptsy rnlrvklsfg ygnftsipwf aflgegqeas
       61 ngiypvilyy kdfdelvlay gisdtnepha qwqfssdipk tiaeyfqats gvypkkygqs
      121 yyacsqkvsq gidytrfasm ldniindykl ifnsgksvip pmsktesycl edalndlfip
      181 ettietilkr ltikkniilq gppgvgktfv arrlaylltg ekapqrvnmv qfhqsysyed
      241 fiqgyrpngv gfrrkdgify nfcqqakeqp ekkyifiide inranlskvf gevmmlmehd
      301 krgenwsvpl tysendeerf yvpenvyiig lmntadrsla vvdyalrrrf sfidiepgfd
      361 tpqfrnflln kkaepsfves lcqkmnelnq eiskeatilg kgfrighsyf ccgledgtsp
      421 dtqwlneivm tdiaplleey ffddpykqqk wtnkllgds