MULTISPECIES: winged helix-turn-helix domain-containing protein

LOCUS       WP_000442141             254 aa            linear   BCT 20-JAN-2025
            [Shigella].
ACCESSION   WP_000442141
VERSION     WP_000442141.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 254)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 254)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   3  (residues 1 to 254)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007860
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..254
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=28504
     Region          7..115
                     /region_name="CadC1"
                     /note="DNA-binding winged helix-turn-helix (wHTH) domain
                     [Transcription]; COG3710"
                     /db_xref="CDD:442924"
ORIGIN      
        1 merrcffiin daiifdpnkc slsnvntqde infpatagci lavllesngg avdrnsiids
       61 vlerfsfdls nntlnqyisl lrksfknigv eenviltipk vgfyisenit iskqsyddsh
      121 lqedvvekve rkrsiplfri lislvvvivi iemfavafkd tysitdyplv ksgkidtcdl
      181 ylsenlneig laksqieaae iskkhlpcvp ganfiydvns mhyllgegqr ylsrcikssn
      241 detyaicsev llyd