S-formylglutathione hydrolase [Escherichia coli].

LOCUS       WP_000419032             277 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_000419032
VERSION     WP_000419032.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 277)
  AUTHORS   Harms,N., Ras,J., Reijnders,W.N., van Spanning,R.J. and
            Stouthamer,A.H.
  TITLE     S-formylglutathione hydrolase of Paracoccus denitrificans is
            homologous to human esterase D: a universal pathway for
            formaldehyde detoxification?
  JOURNAL   J Bacteriol 178 (21), 6296-6299 (1996)
   PUBMED   8892832
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02821.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..277
                     /gene="fghA"
     Protein         1..277
                     /product="S-formylglutathione hydrolase"
                     /EC_number="3.1.2.12"
                     /GO_function="GO:0018738 - S-formylglutathione hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046294 - formaldehyde catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=31117
     Region          2..274
                     /region_name="alpha/beta hydrolases"
                     /note="A functionally diverse superfamily containing
                     proteases, lipases, peroxidases, esterases, epoxide
                     hydrolases and dehalogenases. The catalytic apparatus
                     typically involves three residues (catalytic triad): a
                     serine, a glutamate or aspartate and a...; cl21494"
                     /db_xref="CDD:473884"
     Site            143..147
                     /site_type="active"
                     /note="nucleophilic elbow [active]"
                     /db_xref="CDD:238382"
ORIGIN      
        1 meliekhasf ggwqnvyrhy saslkcemnv gvylppkaag eklpvlywls gltcneqnfi
       61 tksgvqryaa ehniivvapd tsprgshvad adrydlgqga gfylnatqap wnehykmydy
      121 irnelpdlvm nhfpatakks isghsmgglg alvlalrnpd eyvsvsafsp ivspsqvpwg
      181 qqafaaylge nkeawldyhp vslisqgqrv aeimvdqgls ddfyaeqlrt qnlekicqem
      241 niktliryhe gydhsyyfvs sfigehiayh anklnmr