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LOCUS WP_000416454 953 aa linear BCT 28-NOV-2019 ACCESSION WP_000416454 VERSION WP_000416454.1 KEYWORDS RefSeq. SOURCE Vibrio cholerae ORGANISM Vibrio cholerae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio. REFERENCE 1 (residues 1 to 953) AUTHORS Fukunaga,R. and Yokoyama,S. TITLE Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain JOURNAL J. Biol. Chem. 280 (33), 29937-29945 (2005) PUBMED 15970591 REFERENCE 2 (residues 1 to 953) AUTHORS Tardif,K.D. and Horowitz,J. TITLE Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase JOURNAL RNA 10 (3), 493-503 (2004) PUBMED 14970394 REFERENCE 3 (residues 1 to 953) AUTHORS Fukai,S., Nureki,O., Sekine,S., Shimada,A., Vassylyev,D.G. and Yokoyama,S. TITLE Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase JOURNAL RNA 9 (1), 100-111 (2003) PUBMED 12554880 REFERENCE 4 (residues 1 to 953) AUTHORS Hountondji,C., Lazennec,C., Beauvallet,C., Dessen,P., Pernollet,J.C., Plateau,P. and Blanquet,S. TITLE Crucial role of conserved lysine 277 in the fidelity of tRNA aminoacylation by Escherichia coli valyl-tRNA synthetase JOURNAL Biochemistry 41 (50), 14856-14865 (2002) PUBMED 12475234 REFERENCE 5 (residues 1 to 953) AUTHORS Fukai,S., Nureki,O., Sekine,S., Shimada,A., Tao,J., Vassylyev,D.G. and Yokoyama,S. TITLE Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase JOURNAL Cell 103 (5), 793-803 (2000) PUBMED 11114335 REFERENCE 6 (residues 1 to 953) AUTHORS Heck,J.D. and Hatfield,G.W. TITLE Valyl-tRNA synthetase gene of Escherichia coli K12. Primary structure and homology within a family of aminoacyl-TRNA synthetases JOURNAL J. Biol. Chem. 263 (2), 868-877 (1988) PUBMED 3275660 REFERENCE 7 (residues 1 to 953) AUTHORS Hartlein,M., Frank,R. and Madern,D. TITLE Nucleotide sequence of Escherichia coli valyl-tRNA synthetase gene valS JOURNAL Nucleic Acids Res. 15 (21), 9081-9082 (1987) PUBMED 3317277 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF004349.1 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK05729 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..953 /organism="Vibrio cholerae" /db_xref="taxon:666" Protein 1..953 /product="valine--tRNA ligase" /EC_number="6.1.1.9" /GO_function="GO:0000166 - nucleotide binding [Evidence IEA]" /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]" /GO_function="GO:0004832 - valine-tRNA ligase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_process="GO:0006438 - valyl-tRNA aminoacylation [Evidence IEA]" /calculated_mol_wt=108163 Region 1..951 /region_name="ValS" /note="Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; COG0525" /db_xref="CDD:440291" ORIGIN 1 mektynptsi eqdlyktwee qgyfkphgdt skdaysimip ppnvtgslhm ghafqdtimd 61 tlircqrmkg kntlwqvgtd hagiatqmvv erkiaaeegk tkhdygrdaf idkiwewkae 121 sggtitkqlr rlgasvdwdr erftmddgfy kavqevfvrl ykddliyrgk rlvnwdpklh 181 taisdleven ketkghmwhf rypladgvkt adgkdyivva ttrpetmlgd tgvavnpedp 241 rykeligkei ilpivgrrip ivgdehadme kgtgcvkitp ahdfndyevg krhnlpmini 301 ftfdanirda aevfnsngea snaydteipa kyqgmerfaa rkaivakfee lgllqeikdh 361 dltvpygdrg gvviepmltd qwyvragila rpaveaveng diqfvpkqye nmyfswmrdi 421 qdwcisrqlw wghripawyd eqgnvfvgrn eeevraenni aadvalrqdd dvldtwfssa 481 lwtfgtlgwp ektpelkvfh ptdvlvtgfd iiffwvarmi mmtmhfckde dgkaqvpfkt 541 vyvtglirde ngdkmskskg nvldpidmid gidleslvak rtgnmmqpql aakiekntrk 601 tfengieayg tdslrftlaa mastgrdinw dmkrlegyrn fcnklwnasr yvlmnteeqd 661 cgfaagaele ysladkwies qfelaakefn ghidnfrldm aantlyefiw nqfcdwylel 721 tkpvlwkgte aqqratrrtl itvlektlrl ahpvipyite tiwqsvkplv dgvegdtiml 781 qalpqydaan fnqealddie wvkafitsir nlraeydinp gkplevmlka aneqdaarie 841 ankqvlvsla klesirvlad geatpacata lvgkselmip maglidkdae ldrlakeiak 901 tqgeiarieg klgnegfvak apeavitker eklagyqeal vkleqqkati aal