Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: type V toxin-antitoxin system endoribonuclease


LOCUS       WP_000398619              98 aa            linear   BCT 06-JUN-2024
            antitoxin GhoS [Enterobacteriaceae].
ACCESSION   WP_000398619
VERSION     WP_000398619.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 98)
  AUTHORS   Cheng,H.Y., Soo,V.W., Islam,S., McAnulty,M.J., Benedik,M.J. and
            Wood,T.K.
  TITLE     Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell
            membrane to reduce adenosine triphosphate and to reduce growth
            under stress
  JOURNAL   Environ Microbiol 16 (6), 1741-1754 (2014)
   PUBMED   24373067
REFERENCE   2  (residues 1 to 98)
  AUTHORS   Wang,X., Lord,D.M., Cheng,H.Y., Osbourne,D.O., Hong,S.H.,
            Sanchez-Torres,V., Quiroga,C., Zheng,K., Herrmann,T., Peti,W.,
            Benedik,M.J., Page,R. and Wood,T.K.
  TITLE     A new type V toxin-antitoxin system where mRNA for toxin GhoT is
            cleaved by antitoxin GhoS
  JOURNAL   Nat Chem Biol 8 (10), 855-861 (2012)
   PUBMED   22941047
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007589
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..98
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..98
                     /gene="ghoS"
     Protein         1..98
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /EC_number="3.1.26.-"
                     /calculated_mol_wt=11337
     Region          8..94
                     /region_name="GhoS"
                     /note="Endoribonuclease GhoS; pfam11080"
                     /db_xref="CDD:431644"
ORIGIN      
        1 megknkfnty vvsfdypssy ssvflrlrsl mydmnfssiv adeygiprql nensfaitts
       61 laaseiedli rlkcldlpdi dfdlnimtvd dyfrqfyk