MULTISPECIES: SycD/LcrH family type III secretion system chaperone

LOCUS       WP_000386309             165 aa            linear   BCT 06-APR-2020
            SicA [Salmonella].
ACCESSION   WP_000386309
VERSION     WP_000386309.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 165)
  AUTHORS   Darwin,K.H. and Miller,V.L.
  TITLE     Type III secretion chaperone-dependent regulation: activation of
            virulence genes by SicA and InvF in Salmonella typhimurium
  JOURNAL   EMBO J. 20 (8), 1850-1862 (2001)
   PUBMED   11296219
REFERENCE   2  (residues 1 to 165)
  AUTHORS   Tucker,S.C. and Galan,J.E.
  TITLE     Complex function for SicA, a Salmonella enterica serovar
            typhimurium type III secretion-associated chaperone
  JOURNAL   J. Bacteriol. 182 (8), 2262-2268 (2000)
   PUBMED   10735870
REFERENCE   3  (residues 1 to 165)
  AUTHORS   Darwin,K.H. and Miller,V.L.
  TITLE     The putative invasion protein chaperone SicA acts together with
            InvF to activate the expression of Salmonella typhimurium virulence
            genes
  JOURNAL   Mol. Microbiol. 35 (4), 949-960 (2000)
   PUBMED   10692170
REFERENCE   4  (residues 1 to 165)
  AUTHORS   Hermant,D., Menard,R., Arricau,N., Parsot,C. and Popoff,M.Y.
  TITLE     Functional conservation of the Salmonella and Shigella effectors of
            entry into epithelial cells
  JOURNAL   Mol. Microbiol. 17 (4), 781-789 (1995)
   PUBMED   8801431
REFERENCE   5  (residues 1 to 165)
  AUTHORS   Kaniga,K., Tucker,S., Trollinger,D. and Galan,J.E.
  TITLE     Homologs of the Shigella IpaB and IpaC invasins are required for
            Salmonella typhimurium entry into cultured epithelial cells
  JOURNAL   J. Bacteriol. 177 (14), 3965-3971 (1995)
   PUBMED   7608068
REFERENCE   6  (residues 1 to 165)
  AUTHORS   Groisman,E.A. and Ochman,H.
  TITLE     Cognate gene clusters govern invasion of host epithelial cells by
            Salmonella typhimurium and Shigella flexneri
  JOURNAL   EMBO J. 12 (10), 3779-3787 (1993)
   PUBMED   8404849
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000730
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..165
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..165
                     /gene="sicA"
     Protein         1..165
                     /product="SycD/LcrH family type III secretion system
                     chaperone SicA"
                     /calculated_mol_wt=19090
     Region          1..165
                     /region_name="PRK15331"
                     /note="type III secretion system translocator chaperone
                     SicA"
                     /db_xref="CDD:185231"
     Region          40..65
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(41..42,45..46,48,72,75..76,79..80,82..83,106,
                     109..110,113..114,117)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          70..100
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          105..129
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
ORIGIN      
        1 mdyqnnvsee rvaemiwdav segatlkdvh gipqdmmdgl yahayefynq grldeaetff
       61 rflciydfyn pdytmglaav cqlkkqfqka cdlyavaftl lkndyrpvff tgqcqllmrk
      121 aakarqcfel vnertedesl rakalvylea lktaeteqhs eqeke