5-dehydro-4-deoxy-D-glucuronate isomerase [Escherichia coli].

LOCUS       WP_000383257             278 aa            linear   BCT 31-JUL-2023
ACCESSION   WP_000383257
VERSION     WP_000383257.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 278)
  AUTHORS   Reisky,L., Prechoux,A., Zuhlke,M.K., Baumgen,M., Robb,C.S.,
            Gerlach,N., Roret,T., Stanetty,C., Larocque,R., Michel,G., Song,T.,
            Markert,S., Unfried,F., Mihovilovic,M.D., Trautwein-Schult,A.,
            Becher,D., Schweder,T., Bornscheuer,U.T. and Hehemann,J.H.
  TITLE     A marine bacterial enzymatic cascade degrades the algal
            polysaccharide ulvan
  JOURNAL   Nat Chem Biol 15 (8), 803-812 (2019)
   PUBMED   31285597
REFERENCE   2  (residues 1 to 278)
  AUTHORS   Rothe,M., Alpert,C., Loh,G. and Blaut,M.
  TITLE     Novel insights into E. coli's hexuronate metabolism: KduI
            facilitates the conversion of galacturonate and glucuronate under
            osmotic stress conditions
  JOURNAL   PLoS One 8 (2), e56906 (2013)
   PUBMED   23437267
REFERENCE   3  (residues 1 to 278)
  AUTHORS   Lin,J.S. and Shaw,G.C.
  TITLE     Regulation of the kduID operon of Bacillus subtilis by the KdgR
            repressor and the ccpA gene: identification of two KdgR-binding
            sites within the kdgR-kduI intergenic region
  JOURNAL   Microbiology (Reading) 153 (Pt 3), 701-710 (2007)
   PUBMED   17322190
REFERENCE   4  (residues 1 to 278)
  AUTHORS   Crowther,R.L. and Georgiadis,M.M.
  TITLE     The crystal structure of 5-keto-4-deoxyuronate isomerase from
            Escherichia coli
  JOURNAL   Proteins 61 (3), 680-684 (2005)
   PUBMED   16152643
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002091.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00924
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..278
                     /gene="kduI"
     Protein         1..278
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /EC_number="5.3.1.17"
                     /GO_function="GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=30959
     Region          1..278
                     /region_name="PRK00924"
                     /note="5-keto-4-deoxyuronate isomerase; Provisional"
                     /db_xref="CDD:179169"
ORIGIN      
        1 mdvrqsihsa haktletqgl rneflvekvf vadeytmvys hidriiiggi mpvtktvsvg
       61 gevgkqlgvs yflerrelgv iniggagtit vdgqcyeigh rdalyvgkga kevvfasidt
      121 gtpakfyync apahttyptk kvtpdevspv tlgdnltsnr rtinkyfvpd vletcqlsmg
      181 ltelapgnlw ntmpchther rmevyfyfnm dddacvfhmm gqpqetrhiv mhneqavisp
      241 swsihsgvgt kaytfiwgmv genqvfddmd hvavkdlr