MULTISPECIES: NupC/NupG family nucleoside CNT transporter

LOCUS       WP_000382971             416 aa            linear   BCT 17-JAN-2025
            [Escherichia].
ACCESSION   WP_000382971
VERSION     WP_000382971.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 416)
  AUTHORS   Hirschi,M., Johnson,Z.L. and Lee,S.Y.
  TITLE     Visualizing multistep elevator-like transitions of a nucleoside
            transporter
  JOURNAL   Nature 545 (7652), 66-70 (2017)
   PUBMED   28424521
REFERENCE   2  (residues 1 to 416)
  AUTHORS   Johnson,Z.L., Lee,J.H., Lee,K., Lee,M., Kwon,D.Y., Hong,J. and
            Lee,S.Y.
  TITLE     Structural basis of nucleoside and nucleoside drug selectivity by
            concentrative nucleoside transporters
  JOURNAL   Elife 3, e03604 (2014)
   PUBMED   25082345
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 416)
  AUTHORS   Munch-Petersen,A., Mygind,B., Nicolaisen,A. and Pihl,N.J.
  TITLE     Nucleoside transport in cells and membrane vesicles from
            Escherichia coli K12
  JOURNAL   J Biol Chem 254 (10), 3730-3737 (1979)
   PUBMED   374403
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11449426
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     Protein         1..416
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=43265
     Region          1..414
                     /region_name="NupC"
                     /note="Nucleoside permease NupC [Nucleotide transport and
                     metabolism]; COG1972"
                     /db_xref="CDD:441575"
ORIGIN      
        1 mdvmrsvlgm vvlltiafll svnkkkislr tvgaalvlqv viggimlwlp pgrwvaekva
       61 fgvhkvmays dagsafifgs lvgpkmdtlf dgagfifgfr vlpaiifvta lvsilyyigv
      121 mgilirilgg ifqkalnisk iesfvavtti flgqneipai vkpfidrlnr nelftaicsg
      181 masiagstmi gyaalgvpve yllaaslmai pggilfarll spatessqvs fnnlsftetp
      241 pksiieaaat gamtglkiaa gvatvvmafv aiialingii ggvggwfgfe haslesivgy
      301 llaplawvmg vdwsdanlag sligqklain efvaylnfsp ylqtagtlda ktvaiisfal
      361 cgfanfgsig vvvgafsava phrapeiaql glralaaatl snlmsatiag ffigla