crotonobetaine/carnitine-CoA ligase [Shigella flexneri].

LOCUS       WP_000373696             522 aa            linear   BCT 07-MAR-2022
ACCESSION   WP_000373696
VERSION     WP_000373696.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 522)
  AUTHORS   Meadows,J.A. and Wargo,M.J.
  TITLE     Carnitine in bacterial physiology and metabolism
  JOURNAL   Microbiology (Reading) 161 (6), 1161-1174 (2015)
   PUBMED   25787873
REFERENCE   2  (residues 1 to 522)
  AUTHORS   Bernal,V., Arense,P., Blatz,V., Mandrand-Berthelot,M.A., Canovas,M.
            and Iborra,J.L.
  TITLE     Role of betaine:CoA ligase (CaiC) in the activation of betaines and
            the transfer of coenzyme A in Escherichia coli
  JOURNAL   J Appl Microbiol 105 (1), 42-50 (2008)
   PUBMED   18266698
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005947.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08008
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..522
                     /gene="caiC"
     Protein         1..522
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /EC_number="6.2.1.48"
                     /GO_function="GO:0016405 - CoA-ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009437 - carnitine metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=59061
     Region          6..522
                     /region_name="caiC"
                     /note="putative crotonobetaine/carnitine-CoA ligase;
                     Validated; PRK08008"
                     /db_xref="CDD:181195"
ORIGIN      
        1 mdrgamdiig gqhlrqmwdd ladvyghkta licessggvv nrysylelnq einrtanlfy
       61 tlgirkgnkv alhldncpef ifcwfglaki gaimvpinar llreesewil qnsqacllvt
      121 saqfypmyqq iqqedatqlr hicltdvalp addgvssftq lknqqpatlc yapplstddt
      181 aeilftsgtt srpkgvvith ynlrfagyys awqcalrddd vymtvmpafh idcqctaama
      241 afsagatfvl vekysarafw gqaqkyrati tecipmmirt lmvqppsand rqhrlrevmf
      301 ylnlseqekd afcerfgvrl ltsygmteti vgiigdrpsd krrwpsigra gfcyeaeird
      361 dhnrplpage igeicikgvp gktifkeyfl npkatakvle adgwlhtgdt gyrdeegffy
      421 fvdrrcnmik rggenvscve leniiathpk iqdivvvgik dsirdeaika fvvlnegetl
      481 seeeffrfce qnmakfkvps yleirkdlpr ncsgkiirkn lk