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LOCUS WP_000365187 264 aa linear BCT 26-JUL-2024 ACCESSION WP_000365187 VERSION WP_000365187.1 KEYWORDS RefSeq. SOURCE Shigella flexneri ORGANISM Shigella flexneri Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 264) AUTHORS Bazan,J.F., Macdonald,B.T. and He,X. TITLE The TIKI/TraB/PrgY family: a common protease fold for cell signaling from bacteria to metazoa? JOURNAL Dev Cell 25 (3), 225-227 (2013) PUBMED 23673329 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 12999764 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..264 /organism="Shigella flexneri" /db_xref="taxon:623" Protein 1..264 /product="TraB/GumN family protein" /EC_number="3.4.-.-" /GO_function="GO:0008233 - peptidase activity [Evidence IEA]" /calculated_mol_wt=29711 Region 30..264 /region_name="Tiki" /note="Tiki homology domain antagonizes Wnt function via cleavage of amino-terminal residues; cd14789" /db_xref="CDD:350614" ORIGIN 1 mdllyrvktl waalrgnhyt wpaiditlpg nrhshligsi hmgshdmapl ptrllkklkn 61 adaliveadv stsdtpfanl pacealeeri seeqlqnlqh isqemgisps lfstqplwqi 121 amvlqatqaq klglraeygi dyqllqaakq qhkpvieleg aenqiamllq lpdkglalld 181 dtlthwhtna rllqqmmsww lnappqnndi tlpntfsqsl ydvlmhqrnl awrdklramp 241 pgryvvavga lhlygegnlp qmlr