helix-turn-helix domain-containing protein [Escherichia coli].

LOCUS       WP_000361110             194 aa            linear   BCT 18-JUL-2024
ACCESSION   WP_000361110
VERSION     WP_000361110.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 194)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 194)
  AUTHORS   Dunwell,J.M., Purvis,A. and Khuri,S.
  TITLE     Cupins: the most functionally diverse protein superfamily?
  JOURNAL   Phytochemistry 65 (1), 7-17 (2004)
   PUBMED   14697267
REFERENCE   3  (residues 1 to 194)
  AUTHORS   Aravind,L. and Koonin,E.V.
  TITLE     DNA-binding proteins and evolution of transcription regulation in
            the archaea
  JOURNAL   Nucleic Acids Res 27 (23), 4658-4670 (1999)
   PUBMED   10556324
REFERENCE   4  (residues 1 to 194)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 14302692
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..194
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..194
                     /product="helix-turn-helix domain-containing protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=21284
     Region          10..89
                     /region_name="HipB"
                     /note="Transcriptional regulator, contains XRE-family HTH
                     domain [Transcription]; COG1396"
                     /db_xref="CDD:441006"
     Region          99..190
                     /region_name="cupin_XRE_C"
                     /note="XRE (Xenobiotic Response Element) family
                     transcriptional regulators, C-terminal cupin domain;
                     cd02209"
                     /db_xref="CDD:380339"
     Site            order(102,115,117,131,134,138,172,174,187)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:380339"
ORIGIN      
        1 mdkraknqiv dsdiarlllk lrksrnltvt elaqrsgvsq amiskvergt sspsatilsr
       61 lanalnitls klfaelemqq nslvlladqq qhwideetgi trwslspaga cpelikveip
      121 pmgqltipas anehlsgqtl wmlsgsldfr vnhqthhlqa gdclaltfas eyqmrnpdsg
      181 qscsyivafs qknp