MULTISPECIES: LysR family transcriptional regulator

LOCUS       WP_000357790             299 aa            linear   BCT 01-JAN-2025
            [Enterobacteriaceae].
ACCESSION   WP_000357790
VERSION     WP_000357790.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 299)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 299)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444112
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..299
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33199
     Region          4..62
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          92..293
                     /region_name="PBP2_CrgA_like_3"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08472"
                     /db_xref="CDD:176161"
     Site            order(102,106,145,159,161,225,242,269)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176161"
     Site            order(103..104,108..109,111..112,115,119,121..127,188,
                     219..223,230..231,234)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176161"
ORIGIN      
        1 mdkihamqlf ikvaelesfs raadffalpk gsvsrqiqal ehqlgtqllq rttrrvkltp
       61 egmtyyqrak dvlsnlseld glfqqdatsi sgklridipp giakslllpr lseflylhpg
      121 ielelsshdr pvdilhdgfd cvirtgalpe dgviarplgk ltmvncasph yltrfgypqs
      181 pddltshaiv rytphlgvhp lgfevasvng vqwfksggml tvnssenylt aglaglgiiq
      241 ipriavreal ragrlievlp gyraeplsls lvypqrrels rrvnlfmqwl agvmkeyld