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LOCUS WP_000353886 416 aa linear BCT 01-JAN-2025 [Shigella]. ACCESSION WP_000353886 VERSION WP_000353886.1 KEYWORDS RefSeq. SOURCE Shigella ORGANISM Shigella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae. REFERENCE 1 (residues 1 to 416) AUTHORS Hirschi,M., Johnson,Z.L. and Lee,S.Y. TITLE Visualizing multistep elevator-like transitions of a nucleoside transporter JOURNAL Nature 545 (7652), 66-70 (2017) PUBMED 28424521 REFERENCE 2 (residues 1 to 416) AUTHORS Johnson,Z.L., Lee,J.H., Lee,K., Lee,M., Kwon,D.Y., Hong,J. and Lee,S.Y. TITLE Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters JOURNAL Elife 3, e03604 (2014) PUBMED 25082345 REMARK Publication Status: Online-Only REFERENCE 3 (residues 1 to 416) AUTHORS Munch-Petersen,A., Mygind,B., Nicolaisen,A. and Pihl,N.J. TITLE Nucleoside transport in cells and membrane vesicles from Escherichia coli K12 JOURNAL J Biol Chem 254 (10), 3730-3737 (1979) PUBMED 374403 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11449426 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..416 /organism="Shigella" /db_xref="taxon:620" Protein 1..416 /product="NupC/NupG family nucleoside CNT transporter" /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0005337 - nucleoside transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0015293 - symporter activity [Evidence IEA]" /GO_process="GO:1901642 - nucleoside transmembrane transport [Evidence IEA]" /calculated_mol_wt=43223 Region 1..414 /region_name="NupC" /note="Nucleoside permease NupC [Nucleotide transport and metabolism]; COG1972" /db_xref="CDD:441575" ORIGIN 1 mdimrsvvgm vvllaiafll svnkksislr tvgaalllqi aiggimlyfp pgkwaveqaa 61 lgvhkvmsys dagsafifgs lvgpkmdvlf dgagfifafr vlpaiifvta lisllyyigv 121 mgllirilgs ifqkalnisk iesfvavtti flgqneipai vkpfidrvnr nelftaicsg 181 masiagsvmi gyagmgvpid yllaaslmai pggilfaril spatepsqvt fenlsfsetp 241 pksfieaaas gamtglkiaa gvatvvmafv aiialingii ggiggwfgfa naslesifgy 301 vlaplawimg vdwsdanlag sligqklain efvaylsfsp ylqtggtlev ktvaiisfal 361 cgfanfgsig vvvgafsais pkrapeiaql glralaaatl snlmsatiag ffigla