glyoxylate/hydroxypyruvate reductase GhrA [Escherichia coli].

LOCUS       WP_000351284             312 aa            linear   BCT 03-JUN-2019
ACCESSION   WP_000351284
VERSION     WP_000351284.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012013.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK15469
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..312
                     /gene="ghrA"
     Protein         1..312
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /GO_function="GO:0016618 - hydroxypyruvate reductase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030267 - glyoxylate reductase (NADP+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /calculated_mol_wt=35228
     Region          1..312
                     /region_name="ghrA"
                     /note="glyoxylate/hydroxypyruvate reductase GhrA;
                     PRK15469"
                     /db_xref="CDD:185366"
     Site            order(46,64..66,95,227,275)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:240641"
     Site            order(65..66,89,95,99,143..147,165..168,170,197..199,
                     203..204,225..227,251..252,275,277..278,310)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:240641"
     Site            order(98,100..102,104..105,108..109,112,114,117..118,
                     120..121,125..126,128,131,134,158,249,253,256..258,260,
                     264..265,267,270,272..274,276..277,281)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:240641"
ORIGIN      
        1 mdiifyhptf dtqwwiealr kaipqarvra wksgdndsad yalawhppve mlagrdlkav
       61 falgagvdsi lsklqahpem lkpsvplfrl edtgmgeqmq eyavsqvlhw frrfddyriq
      121 qnsshwqplp eyhredftig ilgagvlgsk vaqslqtwrf plrcwsrtrk swpgvqsfag
      181 weelsaflsq crvlinllpn tpetvgiinq qlleklpdga yllnlargvh vveddllaal
      241 dsgkvkgaml dvfnreplpp esplwqhprv titphvaait rpaeaveyis rtiaqlekge
      301 rvcgqvdrar gy