(2E,6E)-farnesyl diphosphate synthase [Escherichia coli].

LOCUS       WP_000347215             299 aa            linear   BCT 28-MAR-2022
ACCESSION   WP_000347215
VERSION     WP_000347215.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007877.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10581
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..299
                     /gene="ispA"
     Protein         1..299
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /EC_number="2.5.1.10"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=32001
     Region          1..299
                     /region_name="PRK10581"
                     /note="(2E,6E)-farnesyl diphosphate synthase"
                     /db_xref="CDD:182567"
     Site            order(76,79..81,83,95..96,158,161,181..182,185,223..224,
                     227,237,242,247)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:173833"
     Site            order(84,94..106,230..231,237..242,245..249)
                     /site_type="active"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     Site            order(223..224,227,237,242,247)
                     /site_type="other"
                     /note="aspartate-rich region 2"
                     /db_xref="CDD:173833"
ORIGIN      
        1 mdfpqqleac vkqanqalsr fiaplpfqnt pvvetmqyga llggkrlrpf lvyatghmfg
       61 vstntldapa aavecihays lihddlpamd dddlrrglpt chvkfgeana ilagdalqtl
      121 afsilsdadm pevsdrdris miselasasg iagmcggqal dldaegkhvp ldalerihrh
      181 ktgaliraav rlgalsagdk grralpvldk yaesiglafq vqddildvvg dtatlgkrqg
      241 adqqlgksty pallgleqar kkaqdlidda rqslkqlaeq sidtsaleal adyiiqrnk