flotillin family protein [Escherichia coli].

LOCUS       WP_000341032             553 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_000341032
VERSION     WP_000341032.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 553)
  AUTHORS   Banning,A., Tomasovic,A. and Tikkanen,R.
  TITLE     Functional aspects of membrane association of reggie/flotillin
            proteins
  JOURNAL   Curr Protein Pept Sci 12 (8), 725-735 (2011)
   PUBMED   22329548
REFERENCE   2  (residues 1 to 553)
  AUTHORS   Browman,D.T., Hoegg,M.B. and Robbins,S.M.
  TITLE     The SPFH domain-containing proteins: more than lipid raft markers
  JOURNAL   Trends Cell Biol 17 (8), 394-402 (2007)
   PUBMED   17766116
REFERENCE   3  (residues 1 to 553)
  AUTHORS   Langhorst,M.F., Reuter,A. and Stuermer,C.A.
  TITLE     Scaffolding microdomains and beyond: the function of
            reggie/flotillin proteins
  JOURNAL   Cell Mol Life Sci 62 (19-20), 2228-2240 (2005)
   PUBMED   16091845
REFERENCE   4  (residues 1 to 553)
  AUTHORS   Morrow,I.C. and Parton,R.G.
  TITLE     Flotillins and the PHB domain protein family: rafts, worms and
            anaesthetics
  JOURNAL   Traffic 6 (9), 725-740 (2005)
   PUBMED   16101677
REFERENCE   5  (residues 1 to 553)
  AUTHORS   Tavernarakis,N., Driscoll,M. and Kyrpides,N.C.
  TITLE     The SPFH domain: implicated in regulating targeted protein turnover
            in stomatins and other membrane-associated proteins
  JOURNAL   Trends Biochem Sci 24 (11), 425-427 (1999)
   PUBMED   10542406
REFERENCE   6  (residues 1 to 553)
  AUTHORS   Bickel,P.E., Scherer,P.E., Schnitzer,J.E., Oh,P., Lisanti,M.P. and
            Lodish,H.F.
  TITLE     Flotillin and epidermal surface antigen define a new family of
            caveolae-associated integral membrane proteins
  JOURNAL   J Biol Chem 272 (21), 13793-13802 (1997)
   PUBMED   9153235
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11455184
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..553
                     /product="flotillin family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0016600 - flotillin complex [Evidence
                     IEA]"
                     /calculated_mol_wt=60553
     Region          13..535
                     /region_name="YqiK"
                     /note="Uncharacterized membrane protein YqiK, contains
                     Band7/PHB/SPFH domain [Function unknown]; COG2268"
                     /db_xref="CDD:441869"
ORIGIN      
        1 mddivnsvps wmftaiiavc ilfiigiifa rlyrrasaeq afvrtglggq kvvmsggaiv
       61 mpifheiipi nmntlklevs rstidslitk drmrvdvvva ffvrvkpsve giataaqtlg
      121 qrtlspedlr mlvedkfvda lrataaqmtm helqdtrenf vqgvqntvae dlsknglele
      181 svsltnfnqt skehfnpnna fdaegltklt qeterrrrer neveqdveva vreknrdals
      241 rkleieqqea fmtleqeqqv ktrtaeqnak iaafeaerrr eaeqtrilae rqiqeteidr
      301 eqavrsrkve aerevrikei eqqqvteian qtksiaiaak seqqsqaear anlalaeavs
      361 aqqnvettrq taeadrakqv aliaaaqdae tkaveltvra kaekeaaemq aaaivelaea
      421 trkkglaeae aqralndain vlsdeqtslk fklallqalp avieksvepm ksidgikiiq
      481 vdglnrggta gdantgnvgg gnlaeqalsa alsyrtqapl idsllneigv sggslaalts
      541 lltpttpvae nve