MULTISPECIES: class Ia ribonucleoside-diphosphate reductase subunit

LOCUS       WP_000332037             376 aa            linear   BCT 01-MAY-2023
            beta [Enterobacteriaceae].
ACCESSION   WP_000332037
VERSION     WP_000332037.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 376)
  AUTHORS   Kolberg,M., Strand,K.R., Graff,P. and Andersson,K.K.
  TITLE     Structure, function, and mechanism of ribonucleotide reductases
  JOURNAL   Biochim Biophys Acta 1699 (1-2), 1-34 (2004)
   PUBMED   15158709
REFERENCE   2  (residues 1 to 376)
  AUTHORS   Eriksson,M., Jordan,A. and Eklund,H.
  TITLE     Structure of Salmonella typhimurium nrdF ribonucleotide reductase
            in its oxidized and reduced forms
  JOURNAL   Biochemistry 37 (38), 13359-13369 (1998)
   PUBMED   9748343
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006576.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09101
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..376
                     /gene="nrdB"
     Protein         1..376
                     /product="class Ia ribonucleoside-diphosphate reductase
                     subunit beta"
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=43386
     Region          1..376
                     /region_name="nrdB"
                     /note="ribonucleotide-diphosphate reductase subunit beta;
                     Reviewed; PRK09101"
                     /db_xref="CDD:181647"
     Site            order(38,45,110..111,114,117..118,121,124,138..139,142)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:153108"
     Site            order(49,85,116,119,123,237..238,242)
                     /site_type="active"
                     /note="putative radical transfer pathway [active]"
                     /db_xref="CDD:153108"
     Site            order(85,116,119,205,239,242)
                     /site_type="other"
                     /note="diiron center [ion binding]"
                     /db_xref="CDD:153108"
     Site            123
                     /site_type="other"
                     /note="tyrosyl radical"
                     /db_xref="CDD:153108"
ORIGIN      
        1 mayttfsqtk ndqlkepmff gqpvnvaryd qqkydifekl iekqlsffwr peevdvsrdr
       61 idyqalpehe khifisnlky qtlldsiqgr spnvallpli sipeletwve twafsetihs
      121 rsythiirni vndpsvvfdd ivtneqiqkr aegissyyde liemtsywhl lgegthtvng
      181 ktvtvslrel kkklylclms vnaleairfy vsfacsfafa erelmegnak iirliardea
      241 lhltgtqhml nllrsgaddp emaeiaeeck qecydlfvqa aqqekdwady lfrdgsmigl
      301 nkdilcqyve yitnirmqav gldlpfqtrs npipwintwl vsdnvqvapq evevssylvg
      361 qidsevdtdd lsnfql