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MULTISPECIES: type II toxin-antitoxin system mRNA interferase RelE


LOCUS       WP_000323025              95 aa            linear   BCT 17-JAN-2025
            [Bacteria].
ACCESSION   WP_000323025
VERSION     WP_000323025.1
KEYWORDS    RefSeq.
SOURCE      Bacteria (eubacteria)
  ORGANISM  Bacteria
            Unclassified.
REFERENCE   1  (residues 1 to 95)
  AUTHORS   Korch,S.B., Malhotra,V., Contreras,H. and Clark-Curtiss,J.E.
  TITLE     The Mycobacterium tuberculosis relBE toxin:antitoxin genes are
            stress-responsive modules that regulate growth through translation
            inhibition
  JOURNAL   J Microbiol 53 (11), 783-795 (2015)
   PUBMED   26502963
  REMARK    Erratum:[J Microbiol. 2015 Dec;53(12):875. PMID: 26626358]
REFERENCE   2  (residues 1 to 95)
  AUTHORS   Li,G.Y., Zhang,Y., Inouye,M. and Ikura,M.
  TITLE     Inhibitory mechanism of Escherichia coli RelE-RelB toxin-antitoxin
            module involves a helix displacement near an mRNA interferase
            active site
  JOURNAL   J Biol Chem 284 (21), 14628-14636 (2009)
   PUBMED   19297318
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006553
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..95
                     /organism="Bacteria"
                     /db_xref="taxon:2"
     gene            1..95
                     /gene="relE"
     Protein         1..95
                     /product="type II toxin-antitoxin system mRNA interferase
                     RelE"
                     /EC_number="3.1.26.-"
                     /calculated_mol_wt=11094
     Region          2..87
                     /region_name="RelE"
                     /note="mRNA-degrading endonuclease RelE, toxin component
                     of the RelBE toxin-antitoxin system [Defense mechanisms];
                     COG2026"
                     /db_xref="CDD:441629"
ORIGIN      
        1 mayfldfder alkewrklgs tvreqlkkkl vevlesprie anklrgmpdc ykiklrssgy
       61 rlvyqvidek vvvfvisvgk rersevysea vkril