MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000288496             417 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_000288496
VERSION     WP_000288496.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 417)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 417)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 417)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022776
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..417
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=45969
     Region          15..388
                     /region_name="MFS_SV2_like"
                     /note="Metazoan Synaptic vesicle glycoprotein 2 (SV2) and
                     related small molecule transporters of the Major
                     Facilitator Superfamily; cd17316"
                     /db_xref="CDD:340874"
     Site            order(25..26,29..30,33,65,115..116,118..120,123,143,
                     146..147,150,223,226..227,230..232,235,263,267,316..317,
                     321,325,341,344..345,348..349,352)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340874"
ORIGIN      
        1 mytplnwttt qrhvafacft swmldafdff ilvfvlsdla ewfhasvsdv siaimltlav
       61 rpigallfgr maekygrrpi lmlnilfftv fellsawspt fmaflifrvm ygvamggiwg
      121 vasslameti pdrsrglmsg ifqagypcgy lfasvifglf ysmvgwrgmf ligalpvvll
      181 pyiwfkvpes pvwlaarark entallpvlr kqwklclylv lvmaffnffs hgtqdlyptf
      241 lkmqhgfdph lisiiaifyn iaamlggify gtlserigrk kaimiaafla lpvlplwafs
      301 sgsftiglga flmqfmvqga wgvvptwlne lvpanaravl pgfvyqlgnl lasvnatlqa
      361 riaethggny glamaivaga vailicvfva fgretrgvvi sgtdsdalpe saishrt