class II holin family protein [Escherichia coli].

LOCUS       WP_000284522              71 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_000284522
VERSION     WP_000284522.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 71)
  AUTHORS   Saier,M.H. Jr. and Reddy,B.L.
  TITLE     Holins in bacteria, eukaryotes, and archaea: multifunctional
            xenologues with potential biotechnological and biomedical
            applications
  JOURNAL   J Bacteriol 197 (1), 7-17 (2015)
   PUBMED   25157079
REFERENCE   2  (residues 1 to 71)
  AUTHORS   Park,T., Struck,D.K., Dankenbring,C.A. and Young,R.
  TITLE     The pinholin of lambdoid phage 21: control of lysis by membrane
            depolarization
  JOURNAL   J Bacteriol 189 (24), 9135-9139 (2007)
   PUBMED   17827300
REFERENCE   3  (residues 1 to 71)
  AUTHORS   Young,R.
  TITLE     Bacteriophage holins: deadly diversity
  JOURNAL   J Mol Microbiol Biotechnol 4 (1), 21-36 (2002)
   PUBMED   11763969
REFERENCE   4  (residues 1 to 71)
  AUTHORS   Wang,I.N., Smith,D.L. and Young,R.
  TITLE     Holins: the protein clocks of bacteriophage infections
  JOURNAL   Annu Rev Microbiol 54, 799-825 (2000)
   PUBMED   11018145
REFERENCE   5  (residues 1 to 71)
  AUTHORS   Barenboim,M., Chang,C.Y., dib Hajj,F. and Young,R.
  TITLE     Characterization of the dual start motif of a class II holin gene
  JOURNAL   Mol Microbiol 32 (4), 715-727 (1999)
   PUBMED   10361276
REFERENCE   6  (residues 1 to 71)
  AUTHORS   Young,R. and Blasi,U.
  TITLE     Holins: form and function in bacteriophage lysis
  JOURNAL   FEMS Microbiol Rev 17 (1-2), 191-205 (1995)
   PUBMED   7669346
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10523107
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..71
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..71
                     /product="class II holin family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /calculated_mol_wt=7905
     Region          5..68
                     /region_name="Phage_holin_2_1"
                     /note="Bacteriophage P21 holin S; pfam04971"
                     /db_xref="CDD:428228"
ORIGIN      
        1 myqmekittg vsyttsavgt gywllqlldk vspsqwvaig vlgsllfgll tyltnlyfki
       61 redrrktarg d