CPBP family intramembrane glutamic endopeptidase [Escherichia

LOCUS       WP_000265265             272 aa            linear   BCT 01-JAN-2025
            coli].
ACCESSION   WP_000265265
VERSION     WP_000265265.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 272)
  AUTHORS   Manolaridis,I., Kulkarni,K., Dodd,R.B., Ogasawara,S., Zhang,Z.,
            Bineva,G., Reilly,N.O., Hanrahan,S.J., Thompson,A.J., Cronin,N.,
            Iwata,S. and Barford,D.
  TITLE     Mechanism of farnesylated CAAX protein processing by the
            intramembrane protease Rce1
  JOURNAL   Nature 504 (7479), 301-305 (2013)
   PUBMED   24291792
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11441430
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..272
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /calculated_mol_wt=30749
     Region          <38..>220
                     /region_name="YfhO"
                     /note="Uncharacterized membrane protein YfhO [Function
                     unknown]; COG4485"
                     /db_xref="CDD:443579"
     Region          169..264
                     /region_name="YdiL"
                     /note="Membrane protease YdiL, CAAX protease family
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG1266"
                     /db_xref="CDD:440877"
ORIGIN      
        1 mwivlvlsls tlswhkvvaf slltvsvvla vlndiidwsv lffvativff iilkfnwkyn
       61 awaksiyevg ivlsaialff hlwpgfhnpv vlnsvtvgpq stpytmyfnf dkalvpfllv
      121 lctsslfkke vksevslwkw galslsvpli lflavffggl kpeihfpewl pefilanlff
      181 vslaeeslfr gyiqsrlsev tsplvaliva allfgfyhys ggallvlfat lsgvvyglsw
      241 mwsgrlwvat lfhfglnlch llfftypflk hn