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L-glyceraldehyde 3-phosphate reductase [Escherichia coli].


LOCUS       WP_000262146             346 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_000262146
VERSION     WP_000262146.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 346)
  AUTHORS   Desai,K.K. and Miller,B.G.
  TITLE     A metabolic bypass of the triosephosphate isomerase reaction
  JOURNAL   Biochemistry 47 (31), 7983-7985 (2008)
   PUBMED   18620424
REFERENCE   2  (residues 1 to 346)
  AUTHORS   Ko,J., Kim,I., Yoo,S., Min,B., Kim,K. and Park,C.
  TITLE     Conversion of methylglyoxal to acetol by Escherichia coli aldo-keto
            reductases
  JOURNAL   J. Bacteriol. 187 (16), 5782-5789 (2005)
   PUBMED   16077126
REFERENCE   3  (residues 1 to 346)
  AUTHORS   Grant,A.W., Steel,G., Waugh,H. and Ellis,E.M.
  TITLE     A novel aldo-keto reductase from Escherichia coli can increase
            resistance to methylglyoxal toxicity
  JOURNAL   FEMS Microbiol. Lett. 218 (1), 93-99 (2003)
   PUBMED   12583903
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008085
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..346
                     /gene="gpr"
     Protein         1..346
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /EC_number="1.1.1.-"
                     /calculated_mol_wt=38684
     Region          1..346
                     /region_name="PRK09912"
                     /note="L-glyceraldehyde 3-phosphate reductase;
                     Provisional"
                     /db_xref="CDD:182140"
     Site            order(31..33,35,61,65..66,100,138,168,193,222..227,231,
                     233,282,299..303,307,310..311)
                     /site_type="active"
                     /db_xref="CDD:381376"
     Site            order(61,66,97,138)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381376"
ORIGIN      
        1 mvwlanpery gqmqyrycgk sglrlpalsl glwhnfghvn alesqrailr kafdlgithf
       61 dlannygppp gsaeenfgrl lredfaayrd eliistkagy dmwpgpygsg gsrkyllasl
      121 dqslkrmgle yvdifyshrv dentpmeeta salahavqsg kalyvgissy spertqkmve
      181 llhewkipll ihqpsynlln rwvdksglld tlqnngvgci aftplaqgll tgkylngipe
      241 dsrmhregnk vrgltpkmlt eanlnslrll nemaqqrgqs maqmalswll kdervtsvlv
      301 gasraeqlee nvqalnnltf steelaqidq hiadgelnlw qassdk