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MULTISPECIES: class II fumarate hydratase [Salmonella].


LOCUS       WP_000259121             467 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_000259121
VERSION     WP_000259121.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00979.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..467
                     /gene="fumC"
     Protein         1..467
                     /product="class II fumarate hydratase"
                     /EC_number="4.2.1.2"
                     /GO_component="GO:0045239 - tricarboxylic acid cycle
                     heteromeric enzyme complex [Evidence IEA]"
                     /GO_function="GO:0004333 - fumarate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=50172
     Region          1..463
                     /region_name="fumC"
                     /note="fumarate hydratase; Reviewed; PRK00485"
                     /db_xref="CDD:234779"
     Site            order(98,100,126,129..132,139..141,188,324,326,331)
                     /site_type="active"
                     /db_xref="CDD:176465"
     Site            order(186..189,193,199..200,206,210,214,232,262..263,266,
                     269..270,272,275..276,279,282..283,286..287,289..290,
                     293..294,344,352,355..357,410)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:176465"
ORIGIN      
        1 mvtvrrekds mgaievpadk lwgaqtqrsl ehfristekm pvslihalal tkraaakvnq
       61 dlgllaaeka saiiqaadev lagkhadefp laiwqtgsgt qsnmnmnevl anraseilgg
      121 vrgmerkvhp nddvnksqss ndvfptamhv aallalrehl ipqlsaltdt lrdkshafad
      181 ivkigrthlq datpltlgqe isgwvamleh nlrhiehslp hvaelalggt avgtglnthp
      241 eyarrvaeel atitaapfvt apnkfealat cdalvqahga lkglaaslmk iandvrwlas
      301 gprcgigeia ipenepgssi mpgkvnptqc eavtmlccqv mgndvainmg gasgnfelnv
      361 yrpmvihnfl qtvrlladgm esfnkhcasg iepnreritq llneslmlvt alnthigydk
      421 aaeiakkahk egltlkasav algylsdeef dawvrpelmv gsmtpgr