Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: PAQR family membrane homeostasis protein TrhA


LOCUS       WP_000250274             219 aa            linear   BCT 16-DEC-2024
            [Enterobacteriaceae].
ACCESSION   WP_000250274
VERSION     WP_000250274.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 219)
  AUTHORS   Melchionna,M., Ganusova,E.E., Harmon,N. and Alexandre,G.
  TITLE     TrhA, a bacterial progestin and adiponectin receptor homolog,
            couples membrane energetics homeostasis and unsaturated fatty acid
            metabolism
  JOURNAL   J Bacteriol 206 (1), e0039723 (2024)
   PUBMED   38054739
REFERENCE   2  (residues 1 to 219)
  AUTHORS   Pilon,M. and Ruiz,M.
  TITLE     PAQR proteins and the evolution of a superpower: Eating all kinds
            of fats: Animals rely on evolutionarily conserved membrane
            homeostasis proteins to compensate for dietary variation
  JOURNAL   Bioessays 45 (9), e2300079 (2023)
   PUBMED   37345585
REFERENCE   3  (residues 1 to 219)
  AUTHORS   Melchionna,M.V., Gullett,J.M., Bouveret,E., Shrestha,H.K.,
            Abraham,P.E., Hettich,R.L. and Alexandre,G.
  TITLE     Bacterial Homologs of Progestin and AdipoQ Receptors (PAQRs) Affect
            Membrane Energetics Homeostasis but Not Fluidity
  JOURNAL   J Bacteriol 204 (4), e0058321 (2022)
   PUBMED   35285724
REFERENCE   4  (residues 1 to 219)
  AUTHORS   Baida,G.E. and Kuzmin,N.P.
  TITLE     Cloning and primary structure of a new hemolysin gene from Bacillus
            cereus
  JOURNAL   Biochim Biophys Acta 1264 (2), 151-154 (1995)
   PUBMED   7495855
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF011669.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK15087
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..219
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..219
                     /gene="trhA"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
     Protein         1..219
                     /product="PAQR family membrane homeostasis protein TrhA"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /calculated_mol_wt=23716
     Region          1..219
                     /region_name="PRK15087"
                     /note="hemolysin; Provisional"
                     /db_xref="CDD:185044"
ORIGIN      
        1 mvqkplikqg yslaeeians vshgiglvfg ivglvlllvq avdlnasata itsyslyggs
       61 millflastl yhaiphqrak mwlkkfdhca iylliagtyt pfllvgldsp larglmiviw
      121 slallgilfk ltiahrfkil slvtylamgw lslvviyema vklaagsvtl lavggvvysl
      181 gvifyvckri pynhaiwhgf vlggsvchfl aiylyigqa