penicillin-binding protein activator LpoA [Escherichia coli].

LOCUS       WP_000249209             678 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_000249209
VERSION     WP_000249209.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 678)
  AUTHORS   Paradis-Bleau,C., Markovski,M., Uehara,T., Lupoli,T.J., Walker,S.,
            Kahne,D.E. and Bernhardt,T.G.
  TITLE     Lipoprotein cofactors located in the outer membrane activate
            bacterial cell wall polymerases
  JOURNAL   Cell 143 (7), 1110-1120 (2010)
   PUBMED   21183074
REFERENCE   2  (residues 1 to 678)
  AUTHORS   Typas,A., Banzhaf,M., van den Berg van Saparoea,B., Verheul,J.,
            Biboy,J., Nichols,R.J., Zietek,M., Beilharz,K., Kannenberg,K., von
            Rechenberg,M., Breukink,E., den Blaauwen,T., Gross,C.A. and
            Vollmer,W.
  TITLE     Regulation of peptidoglycan synthesis by outer-membrane proteins
  JOURNAL   Cell 143 (7), 1097-1109 (2010)
   PUBMED   21183073
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011236
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..678
                     /gene="lpoA"
     Protein         1..678
                     /product="penicillin-binding protein activator LpoA"
                     /calculated_mol_wt=72680
     Region          1..678
                     /region_name="LpoA"
                     /note="Outer membrane lipoprotein LpoA, binds and
                     activates PBP1a [Cell wall/membrane/envelope biogenesis];
                     COG3107"
                     /db_xref="CDD:442341"
     Region          66..92
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276808"
     Region          99..127
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276808"
ORIGIN      
        1 mvpstfsrlk aarclpvvla alifvgcgth tpdqstaymq gtaqadsafy lqqmqqssdd
       61 trinwqllai ralvkegktg qavelfnqlp qelndsqrre ktllaveikl aqkdfagaqn
      121 llakitpadl eqnqqarywq akidasqgrp sidllralia qepllgakek qqnidatwqa
      181 lssmtqeqan tlvinadeni lqgwldlqrv wfdnrndpdm mkagiadwqk rypnnpgakm
      241 lptqlvnvka fkpastnkia lllplngqaa vfgrtiqqgf eaaknigtqp vaaqvaaapa
      301 advaeqpqpq tadgvaspaq asvsdltgdq paaqpvpvsa patstaavsa panpsaelki
      361 ydtssqplsq ilsqvqqdga sivvgpllkn nveellksnt plnvlalnqp enienrvnic
      421 yfalspedea rdaarhirdq gkqaplvlip rsslgdrvan afaqewqklg ggtvlqqkfg
      481 stselragvn ggsgialtgt pitprattds gmttnnptlq ttptddqftn nggrvdavyi
      541 vatpgeiafi kpmiamrngs qsgatlyass rsaqgtagpd frlemeglqy seipmlaggn
      601 lplmqqalsa vnndyslarm yamgvdawsl anhfsqmrqv qgfeingntg sltanpdcvi
      661 nrklswlqyq qgqvvpas