MULTISPECIES: class 1b ribonucleoside-diphosphate reductase subunit

LOCUS       WP_000246534             714 aa            linear   BCT 20-NOV-2023
            alpha [Escherichia].
ACCESSION   WP_000246534
VERSION     WP_000246534.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 714)
  AUTHORS   Zhang,Y. and Stubbe,J.
  TITLE     Bacillus subtilis class Ib ribonucleotide reductase is a
            dimanganese(III)-tyrosyl radical enzyme
  JOURNAL   Biochemistry 50 (25), 5615-5623 (2011)
   PUBMED   21561096
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..714
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..714
                     /gene="nrdE"
     Protein         1..714
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /calculated_mol_wt=80348
     Region          15..714
                     /region_name="RNR_1b_NrdE"
                     /note="ribonucleoside-diphosphate reductase, class 1b,
                     alpha subunit; TIGR04170"
                     /db_xref="CDD:211905"
ORIGIN      
        1 matttaeclt qetmdyhaln amlnlydsag riqfdkdrqa vdafiathvr pnsvtfssqq
       61 qrlnwlvneg yydesvlnry srdfvitlft hahtsgfrfq tflgawkfyt sytlktfdgk
      121 ryledfadrv tmvaltlaqg detlalqltd emlsgrfqpa tptflncgkq qrgelvscfl
      181 lriednmesi gravnsalql skrgggvafl lsnlreagap ikrienqssg vipvmkmled
      241 afsyanqlga rqgagavylh ahhpdilrfl dtkrenadek iriktlslgv vipditfhla
      301 kenaqmalfs pydvervygk pfadvaisqh ydelvaderi rkkylnardf fqrlaeiqfe
      361 sgypyimyed tvnranpiag rinmsnlcse ilqvnsasey denldytrtg hdiscnlgsl
      421 niahtmdspd fartvetavr gltavsdmsh irsvpsieag naashaiglg qmnlhgylar
      481 egiaygspea ldftnlyfya itwhalrtsm llarergetf agfkqsryas geyfsqylqg
      541 nwqpktakvg elftrsgitl ptremwaqlr ddvmrygiyn qnlqavpptg sisyinhats
      601 sihpivakve irkegktgrv yypapfmtne nlalyqdaye igaekiidty aeatrhvdqg
      661 lsltlffpdt attrdinkaq iyawrkgikt lyyirlrqma legteiegcv scal