MULTISPECIES: SPI-1 type III secretion system needle tip complex

LOCUS       WP_000245788             593 aa            linear   BCT 10-JUL-2019
            protein SipB [Salmonella].
ACCESSION   WP_000245788
VERSION     WP_000245788.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 593)
  AUTHORS   Hernandez,L.D., Pypaert,M., Flavell,R.A. and Galan,J.E.
  TITLE     A Salmonella protein causes macrophage cell death by inducing
            autophagy
  JOURNAL   J. Cell Biol. 163 (5), 1123-1131 (2003)
   PUBMED   14662750
REFERENCE   2  (residues 1 to 593)
  AUTHORS   Kubori,T. and Galan,J.E.
  TITLE     Salmonella type III secretion-associated protein InvE controls
            translocation of effector proteins into host cells
  JOURNAL   J. Bacteriol. 184 (17), 4699-4708 (2002)
   PUBMED   12169593
REFERENCE   3  (residues 1 to 593)
  AUTHORS   McGhie,E.J., Hume,P.J., Hayward,R.D., Torres,J. and Koronakis,V.
  TITLE     Topology of the Salmonella invasion protein SipB in a model bilayer
  JOURNAL   Mol. Microbiol. 44 (5), 1309-1321 (2002)
   PUBMED   12068811
REFERENCE   4  (residues 1 to 593)
  AUTHORS   Scherer,C.A., Cooper,E. and Miller,S.I.
  TITLE     The Salmonella type III secretion translocon protein SspC is
            inserted into the epithelial cell plasma membrane upon infection
  JOURNAL   Mol. Microbiol. 37 (5), 1133-1145 (2000)
   PUBMED   10972831
REFERENCE   5  (residues 1 to 593)
  AUTHORS   Hayward,R.D., McGhie,E.J. and Koronakis,V.
  TITLE     Membrane fusion activity of purified SipB, a Salmonella surface
            protein essential for mammalian cell invasion
  JOURNAL   Mol. Microbiol. 37 (4), 727-739 (2000)
   PUBMED   10972796
REFERENCE   6  (residues 1 to 593)
  AUTHORS   Hersh,D., Monack,D.M., Smith,M.R., Ghori,N., Falkow,S. and
            Zychlinsky,A.
  TITLE     The Salmonella invasin SipB induces macrophage apoptosis by binding
            to caspase-1
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 96 (5), 2396-2401 (1999)
   PUBMED   10051653
REFERENCE   7  (residues 1 to 593)
  AUTHORS   Hueck,C.J., Hantman,M.J., Bajaj,V., Johnston,C., Lee,C.A. and
            Miller,S.I.
  TITLE     Salmonella typhimurium secreted invasion determinants are
            homologous to Shigella Ipa proteins
  JOURNAL   Mol. Microbiol. 18 (3), 479-490 (1995)
   PUBMED   8748032
REFERENCE   8  (residues 1 to 593)
  AUTHORS   Hermant,D., Menard,R., Arricau,N., Parsot,C. and Popoff,M.Y.
  TITLE     Functional conservation of the Salmonella and Shigella effectors of
            entry into epithelial cells
  JOURNAL   Mol. Microbiol. 17 (4), 781-789 (1995)
   PUBMED   8801431
REFERENCE   9  (residues 1 to 593)
  AUTHORS   Kaniga,K., Tucker,S., Trollinger,D. and Galan,J.E.
  TITLE     Homologs of the Shigella IpaB and IpaC invasins are required for
            Salmonella typhimurium entry into cultured epithelial cells
  JOURNAL   J. Bacteriol. 177 (14), 3965-3971 (1995)
   PUBMED   7608068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000657
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..593
                     /gene="sipB"
     Protein         1..593
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipB"
                     /calculated_mol_wt=62320
     Region          1..593
                     /region_name="PRK15374"
                     /note="type III secretion system needle tip complex
                     protein SipB"
                     /db_xref="CDD:185272"
ORIGIN      
        1 mvndassisr sgytqnprla eaafegvrkn tdflkaadka fkdvvatkag dlkagtksge
       61 saintvglkp ptdaarekls segqltlllg klmtllgdvs lsqlesrlav wqamiesqke
      121 mgiqvskefq talgeaqeat dlyeasikkt dtaksvydaa tkkltqaqnk lqsldpadpg
      181 yaqaeaaveq agkeateake aldkatdatv kagtdakaka ekadniltkf qgtanaasqn
      241 qvsqgeqdnl snvarltmlm amfieivgkn teeslqndla lfnalqegrq aemekksaef
      301 qeetrkaeet nrimgcigkv lgalltivsv vaavftggas lalaavglav mvadeivkaa
      361 tgvsfiqqal npimehvlkp lmeligkait kaleglgvdk ktaemagsiv gaivaaiamv
      421 avivvvavvg kgaaaklgna lskmmgetik klvpnvlkql aqngsklftq gmqritsglg
      481 nvgskmglqt nalskelvgn tlnkvalgme vtntaaqsag gvaegvfikn asealadfml
      541 arfamdqiqq wlkqsveifg enqkvtaelq kamssavqqn adasrfilrq sra