Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: endoribonuclease toxin ChpB [Enterobacteriaceae].


LOCUS       WP_000239577             116 aa            linear   BCT 06-OCT-2020
ACCESSION   WP_000239577
VERSION     WP_000239577.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 116)
  AUTHORS   Belitsky,M., Avshalom,H., Erental,A., Yelin,I., Kumar,S.,
            London,N., Sperber,M., Schueler-Furman,O. and Engelberg-Kulka,H.
  TITLE     The Escherichia coli extracellular death factor EDF induces the
            endoribonucleolytic activities of the toxins MazF and ChpBK
  JOURNAL   Mol. Cell 41 (6), 625-635 (2011)
   PUBMED   21419338
REFERENCE   2  (residues 1 to 116)
  AUTHORS   Kamphuis,M.B., Bonvin,A.M., Monti,M.C., Lemonnier,M.,
            Munoz-Gomez,A., van den Heuvel,R.H., Diaz-Orejas,R. and Boelens,R.
  TITLE     Model for RNA binding and the catalytic site of the RNase Kid of
            the bacterial parD toxin-antitoxin system
  JOURNAL   J. Mol. Biol. 357 (1), 115-126 (2006)
   PUBMED   16413033
REFERENCE   3  (residues 1 to 116)
  AUTHORS   Christensen,S.K., Pedersen,K., Hansen,F.G. and Gerdes,K.
  TITLE     Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and
            ChpBK cleave translated RNAs and are counteracted by tmRNA
  JOURNAL   J. Mol. Biol. 332 (4), 809-819 (2003)
   PUBMED   12972253
REFERENCE   4  (residues 1 to 116)
  AUTHORS   Masuda,Y., Miyakawa,K., Nishimura,Y. and Ohtsubo,E.
  TITLE     chpA and chpB, Escherichia coli chromosomal homologs of the pem
            locus responsible for stable maintenance of plasmid R100
  JOURNAL   J. Bacteriol. 175 (21), 6850-6856 (1993)
   PUBMED   8226627
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007791
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..116
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..116
                     /gene="chpB"
     Protein         1..116
                     /product="endoribonuclease toxin ChpB"
                     /EC_number="4.6.1.22"
                     /calculated_mol_wt=12361
     Region          1..116
                     /region_name="PRK09812"
                     /note="type II toxin-antitoxin system ChpB family toxin"
                     /db_xref="CDD:182089"
ORIGIN      
        1 mvkkseferg divlvgfdpa sgheqqgagr palvlsvqaf nqlgmtlvap itqggnfary
       61 agfsvplhce egdvhgvvlv nqvrmmdlha rlakriglaa devveeallr lqavve