Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

envelope stress response activation lipoprotein NlpE [Escherichia


LOCUS       WP_000239181             236 aa            linear   BCT 08-JUN-2023
            coli].
ACCESSION   WP_000239181
VERSION     WP_000239181.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 236)
  AUTHORS   Delhaye,A., Laloux,G. and Collet,J.F.
  TITLE     The Lipoprotein NlpE Is a Cpx Sensor That Serves as a Sentinel for
            Protein Sorting and Folding Defects in the Escherichia coli
            Envelope
  JOURNAL   J. Bacteriol. 201 (10) (2019)
   PUBMED   30833359
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            NlpE, an outer membrane lipoprotein, interacts directly with CpxA,
            the sensor histidine kinase of the Cpx system for response to
            envelope stress.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007814.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10523
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..236
                     /gene="nlpE"
                     /gene_synonym="cutF"
     Protein         1..236
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /calculated_mol_wt=25723
     Region          1..233
                     /region_name="PRK10523"
                     /note="envelope stress response activation lipoprotein
                     NlpE"
                     /db_xref="CDD:236708"
ORIGIN      
        1 mvkkaivtam avislftlmg cnnraevdtl spaqaaelkp mpqswrgvlp cadcegiets
       61 lflekdgtwv mnerylgare epssfasygt wartadklvl tdskgeksyy rakgdaleml
      121 dregnpiesq fnytlepaqs slpmtpmtlr gmyfymadaa tftdcatgkr fmvannaele
      181 rgylaarghs ekpvllsveg hftleanpdt gaptkvlapd tagkfypnqd csslgq