MULTISPECIES: bifunctional chorismate mutase/prephenate

LOCUS       WP_000225229             373 aa            linear   BCT 16-DEC-2020
            dehydrogenase [Enterobacteriaceae].
ACCESSION   WP_000225229
VERSION     WP_000225229.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 373)
  AUTHORS   Chiu,H.J., Abdubek,P., Astakhova,T., Axelrod,H.L., Carlton,D.,
            Clayton,T., Das,D., Deller,M.C., Duan,L., Feuerhelm,J., Grant,J.C.,
            Grzechnik,A., Han,G.W., Jaroszewski,L., Jin,K.K., Klock,H.E.,
            Knuth,M.W., Kozbial,P., Krishna,S.S., Kumar,A., Marciano,D.,
            McMullan,D., Miller,M.D., Morse,A.T., Nigoghossian,E., Okach,L.,
            Reyes,R., Tien,H.J., Trame,C.B., van den Bedem,H., Weekes,D.,
            Xu,Q., Hodgson,K.O., Wooley,J., Elsliger,M.A., Deacon,A.M.,
            Godzik,A., Lesley,S.A. and Wilson,I.A.
  TITLE     The structure of Haemophilus influenzae prephenate dehydrogenase
            suggests unique features of bifunctional TyrA enzymes
  JOURNAL   Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (Pt 10),
            1317-1325 (2010)
   PUBMED   20944228
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008400.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11199
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..373
                     /gene="tyrA"
     Protein         1..373
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /GO_function="GO:0004106 - chorismate mutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004665 - prephenate dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_function="GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41912
     Region          1..373
                     /region_name="tyrA"
                     /note="bifunctional chorismate mutase/prephenate
                     dehydrogenase; Provisional; PRK11199"
                     /db_xref="CDD:183035"
ORIGIN      
        1 mvaeltalrd qidevdkall nllakrlelv aevgevksrf glpiyvpere asmlasrrae
       61 aealgvppdl iedvlrrvmr esyssendkg fktlcpslrp vvivggggqm grlfekmltl
      121 sgyqvrileq hdwdraadiv adagmvivsv pihvteqvig klpplpkdci lvdlasvkng
      181 plqamlvahd gpvlglhpmf gpdsgslakq vvvwcdgrkp eayqwfleqi qvwgarlhri
      241 savehdqnma fiqalrhfat fayglhlaee nvqleqllal sspiyrlela mvgrlfaqdp
      301 qlyadiimss ernlalikry ykrfgeaiel leqgdkqafi dsfrkvehwf gdyaqrfqse
      361 srvllrqand nrq