MULTISPECIES: UMP kinase [Enterobacteriaceae].

LOCUS       WP_000224573             241 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_000224573
VERSION     WP_000224573.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 241)
  AUTHORS   Evrin,C., Straut,M., Slavova-Azmanova,N., Bucurenci,N., Onu,A.,
            Assairi,L., Ionescu,M., Palibroda,N., Barzu,O. and Gilles,A.M.
  TITLE     Regulatory mechanisms differ in UMP kinases from gram-negative and
            gram-positive bacteria
  JOURNAL   J Biol Chem 282 (10), 7242-7253 (2007)
   PUBMED   17210578
REFERENCE   2  (residues 1 to 241)
  AUTHORS   Briozzo,P., Evrin,C., Meyer,P., Assairi,L., Joly,N., Barzu,O. and
            Gilles,A.M.
  TITLE     Structure of Escherichia coli UMP kinase differs from that of other
            nucleoside monophosphate kinases and sheds new light on enzyme
            regulation
  JOURNAL   J Biol Chem 280 (27), 25533-25540 (2005)
   PUBMED   15857829
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02075.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..241
                     /gene="pyrH"
     Protein         1..241
                     /product="UMP kinase"
                     /EC_number="2.7.4.22"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0033862 - UMP kinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /calculated_mol_wt=25839
     Region          5..241
                     /region_name="PyrH"
                     /note="Uridylate kinase [Nucleotide transport and
                     metabolism]; COG0528"
                     /db_xref="CDD:440294"
ORIGIN      
        1 matnakpvyk rillklsgea lqgtegfgid asildrmaqe ikelvelgiq vgvvigggnl
       61 frgaglakag mnrvvgdhmg mlatvmngla mrdalhrayv narlmsaipl ngvcdsyswa
      121 eaisllrnnr vvilsagtgn pffttdsaac lrgieieadv vlkatkvdgv ftadpakdpt
      181 atmyeqltys evlekelkvm dlaaftlard hklpirvfnm nkpgalrrvv mgekegtlit
      241 e